Bladder Perforation Secondary to Primary Systemic Amyloidosis

Abstract EN

Amyloidosis is a disorder of protein folding characterized by extracellular aggregation and deposition of amyloid protein fibrils.

Light-chain amyloidosis, also known as primary systemic amyloidosis, is the most common form of the disease.

We present a case of an 84-year-old male with a history of systemic primary amyloidosis causing genitourinary, cardiac, and autonomic dysfunction who presented with hematuria and hypotension secondary to bladder perforation.

He underwent open repair of a large extraperitoneal bladder defect.

He ultimately died as a result of medical complications from his disease.