Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides
Joint Authors
Chen, Fengyang
Zhang, Lin
Zong, Shuling
Xu, Shifang
Li, Xiaoyu
Ye, Yiping
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-17
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Metasequoia glyptostroboides Hu et Cheng is the only living species in the genus Metasequoia Miki ex Hu et Cheng (Taxodiaceae), which is well known as a “living fossil” species.
In the Chinese folk medicine, the leaves and bark of M.
glyptostroboides are used as antimicrobic, analgesic, and anti-inflammatory drug for dermatic diseases.
This study is the first to report the free radical scavenging capacity, antioxidant activity, and proanthocyanidin composition of the bark of M.
glyptostroboides.
We observed total of six extracts and fractions, which were easily obtained by water-ethanol extraction and followed by a further separation with D101 resin column chromatography, had significant DPPH radical, superoxide anion radical, and hydroxyl radical scavenging capacity, total antioxidative capacity (T-AOC), lipid peroxidation inhibitory activity, and metal ions chelating capacity.
The fraction MGEB, which was obtained by 60% ethanol extraction and followed by a further separation with D101 resin column chromatograph, possessed the highest proanthocyanidin content and the highest free radical scavenging and antioxidant activities.
Furthermore, MGEB could significantly protect against CCl4 induced acute liver injury through inhibition of oxidative stress in mice.
In addition, ten proanthocyanidins were isolated from MGEB, and six of them were firstly reported from this plant.
American Psychological Association (APA)
Chen, Fengyang& Zhang, Lin& Zong, Shuling& Xu, Shifang& Li, Xiaoyu& Ye, Yiping. 2014. Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1018124
Modern Language Association (MLA)
Chen, Fengyang…[et al.]. Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1018124
American Medical Association (AMA)
Chen, Fengyang& Zhang, Lin& Zong, Shuling& Xu, Shifang& Li, Xiaoyu& Ye, Yiping. Antioxidant Capacity and Proanthocyanidin Composition of the Bark of Metasequoia glyptostroboides. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1018124
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018124