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Wild Mushrooms in Nepal: Some Potential Candidates as Antioxidant and ACE-Inhibition Sources
Joint Authors
Hai Bang, Tran
Suhara, Hiroto
Doi, Katsumi
Ishikawa, Hiroya
Fukami, Katsuya
Parajuli, Gopal Prasad
Katakura, Yoshinori
Yamashita, Shuntaro
Watanabe, Kazuo
Adhikari, Mahesh Kumar
Manandhar, Hira Kaji
Kondo, Ryuichiro
Shimizu, Kuniyoshi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Twenty-nine mushrooms collected in the mountainous areas of Nepal were analyzed for antioxidant activity by different methods, including Folin-Ciocalteu, ORAC, ABTS, and DPPH assays.
Intracellular H2O2-scavenging activity was also performed on HaCaT cells.
The results showed that phenolic compounds are the main antioxidant of the mushrooms.
Among studied samples, Inonotus andersonii, and Phellinus gilvus exhibited very high antioxidant activity with the phenolic contents up to 310.8 and 258.7 mg GAE/g extracts, respectively.
The H2O2-scavenging assay on cells also revealed the potential of these mushrooms in the prevention of oxidative stress.
In term of ACE-inhibition, results showed that Phlebia tremellosa would be a novel and promising candidate for antihypertensive studies.
This mushroom exhibited even higher in vitro ACE-inhibition activity than Ganoderma lingzhi, with the IC50 values of the two mushrooms being 32 μg/mL and 2 μg/mL, respectively.
This is the first time biological activities of mushrooms collected in Nepal were reported.
Information from this study should be a valuable reference for future studies on antioxidant and ACE-inhibitory activities of mushrooms.
American Psychological Association (APA)
Hai Bang, Tran& Suhara, Hiroto& Doi, Katsumi& Ishikawa, Hiroya& Fukami, Katsuya& Parajuli, Gopal Prasad…[et al.]. 2014. Wild Mushrooms in Nepal: Some Potential Candidates as Antioxidant and ACE-Inhibition Sources. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1018216
Modern Language Association (MLA)
Hai Bang, Tran…[et al.]. Wild Mushrooms in Nepal: Some Potential Candidates as Antioxidant and ACE-Inhibition Sources. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1018216
American Medical Association (AMA)
Hai Bang, Tran& Suhara, Hiroto& Doi, Katsumi& Ishikawa, Hiroya& Fukami, Katsuya& Parajuli, Gopal Prasad…[et al.]. Wild Mushrooms in Nepal: Some Potential Candidates as Antioxidant and ACE-Inhibition Sources. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1018216
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018216