Effects of Nigella sativa (Habbatus sauda) Oil and Nicotine Chronic Treatments on Sperm Parameters and Testis Histological Features of Rats
Joint Authors
Cho Ping, Ng
Hashim, Noor Hashida
Hasan Adli, Durriyyah Sharifah
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Twenty-four Sprague-Dawley male rats (7–9 weeks old, 200–250 g) were divided into Nicotine (N) (0.5 mg/100 g body weight (BW), Nicotine Control (NC) (saline, 0.1 mL/100 g BW), Habbatus sauda oil (HS) (6.0 μL/100 g BW), and Habbatus sauda Control (HSC) (corn oil, 0.1 mL/100 g BW) groups and treated for 100 days.
Sperm parameters and seminiferous tubules measurements were evaluated.
The N showed a significantly lower sperm motility ( 1.03 ± 0.05 × 10 6 sperm/mL) and percentage of normal ( 82.61 ± 0.03 %) and live ( 93.88 ± 0.01 %) sperm, higher value for the seminiferous tubule ( 253.36 ± 1.83 μm) and lumen ( 100.15 ± 2.38 μm) diameters and spermatogonia ( 19.85 ± 0.39 μm) and spermatocytes ( 33.37 ± 0.59 μm) layers, and thinner spermatid-sperm layer ( 22.14 ± 0.71 μm) than the NC ( P < 0.05 ).
The HS had significantly higher sperm motility ( 1.49 ± 0.04 × 10 6 sperm/mL) and percentage of normal ( 90.61 ± 0.01 %) and live ( 96.98 ± 0.01 %) sperm, smaller lumen diameter ( 67.53 ± 2.34 μm) and thinner spermatogonia ( 17.67 ± 0.32 μm) and wider spermatid-sperm ( 36.95 ± 0.79 μm) layers than the HSC ( P < 0.05 ).
This research confirmed that nicotine reduced sperm motility and morphology of normal and live sperms and also affected the testis histology, while Habbatus sauda oil increased sperm quality and gave better testis histological features.
American Psychological Association (APA)
Cho Ping, Ng& Hashim, Noor Hashida& Hasan Adli, Durriyyah Sharifah. 2014. Effects of Nigella sativa (Habbatus sauda) Oil and Nicotine Chronic Treatments on Sperm Parameters and Testis Histological Features of Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1018251
Modern Language Association (MLA)
Cho Ping, Ng…[et al.]. Effects of Nigella sativa (Habbatus sauda) Oil and Nicotine Chronic Treatments on Sperm Parameters and Testis Histological Features of Rats. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1018251
American Medical Association (AMA)
Cho Ping, Ng& Hashim, Noor Hashida& Hasan Adli, Durriyyah Sharifah. Effects of Nigella sativa (Habbatus sauda) Oil and Nicotine Chronic Treatments on Sperm Parameters and Testis Histological Features of Rats. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1018251
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018251