Compound Danshen Dripping Pill Pretreatment to Prevent Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Joint Authors
Yang, Rong
Chang, Liang
Guo, Bing-yan
Wang, Yan-wei
Wang, Ya-ling
Jin, Xin
Liu, Su-yun
Li, Yong-jun
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Contrast-induced nephropathy (CIN) limits the outcome of percutaneous coronary intervention (PCI).
Objective.
To investigate whether pretreatment with Compound Danshen Dripping Pills (CDDP) will decrease the incidence of CIN after PCI.
Methods.
A total of 229 patients with acute coronary syndrome (ACS) undergoing PCI were divided into the control group (n=114) and the CDDP (containing salvia miltiorrhiza and sanqi) group (n=115; given 20 CDDP pills, three times daily before PCI).
Serum creatinine, creatinine clearance (CrCl), high-sensitivity C-reactive protein (hsCRP), P-selectin, and intercellular adhesion molecule-1 (ICAM-1) were measured at admission and 24 and 48 h after PCI.
Results.
CrCl decreased after PCI but recovered after 48 h.
In the CDDP group, CrCl recovered more rapidly (P<0.05).
The procedure increased the hsCRP, P-selectin, and ICAM-1 levels, but these levels were less in the CDDP group (P<0.05).
Conclusions.
Pretreatment with CDDP can decrease the occurrence of CIN in patients undergoing PCI, suggesting that the early use of CDDP is an appropriate adjuvant pharmacological therapy before PCI.
American Psychological Association (APA)
Yang, Rong& Chang, Liang& Guo, Bing-yan& Wang, Yan-wei& Wang, Ya-ling& Jin, Xin…[et al.]. 2014. Compound Danshen Dripping Pill Pretreatment to Prevent Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1018295
Modern Language Association (MLA)
Yang, Rong…[et al.]. Compound Danshen Dripping Pill Pretreatment to Prevent Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1018295
American Medical Association (AMA)
Yang, Rong& Chang, Liang& Guo, Bing-yan& Wang, Yan-wei& Wang, Ya-ling& Jin, Xin…[et al.]. Compound Danshen Dripping Pill Pretreatment to Prevent Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1018295
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018295