Antimutagenicity of Methanolic Extracts from Anemopsis californica in Relation to Their Antioxidant Activity
Joint Authors
Del-Toro-Sánchez, Carmen Lizette
Bautista-Bautista, Nereyda
Blasco-Cabal, José Luis
Gonzalez-Ávila, Marisela
Gutiérrez-Lomelí, Melesio
Arriaga-Alba, Myriam
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Anemopsis californica has been used empirically to treat infectious diseases.
However, there are no antimutagenic evaluation reports on this plant.
The present study evaluated the antioxidant activity in relation to the mutagenic and antimutagenic activity properties of leaf (LME) and stem (SME) methanolic extracts of A.
californica collected in the central Mexican state of Querétaro.
Antioxidant properties and total phenols of extracts were evaluated using DPPH (1,1-diphenyl-2-picrylhydrazyl) and Folin-Ciocalteu methods, respectively.
Mutagenicity was evaluated using the Ames test employing Salmonella enterica serovar Typhimurium strains (TA98, TA100, and TA102), with and without an aroclor 1254 (S9 mixture).
Antimutagenesis was performed against mutations induced on the Ames test with MNNG, 2AA, or 4NQO.
SME presented the highest antioxidant capacity and total phenolic content.
None of the extracts exhibited mutagenicity in the Ames test.
The extracts produced a significant reduction in 2AA-induced mutations in S.
typhimurium TA98.
In both extracts, mutagenesis induced by 4NQO or methyl-N′-nitro-N-nitrosoguanidine (MNNG) was reduced only if the exposure of strains was <10 μg/Petri dish.
A.
californca antioxidant properties and its capacity to reduce point mutations render it suitable to enhance medical cancer treatments.
The significant effect against antimutagenic 2AA suggests that their consumption would provide protection against carcinogenic polycyclic aromatic compounds.
American Psychological Association (APA)
Del-Toro-Sánchez, Carmen Lizette& Bautista-Bautista, Nereyda& Blasco-Cabal, José Luis& Gonzalez-Ávila, Marisela& Gutiérrez-Lomelí, Melesio& Arriaga-Alba, Myriam. 2014. Antimutagenicity of Methanolic Extracts from Anemopsis californica in Relation to Their Antioxidant Activity. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1018316
Modern Language Association (MLA)
Del-Toro-Sánchez, Carmen Lizette…[et al.]. Antimutagenicity of Methanolic Extracts from Anemopsis californica in Relation to Their Antioxidant Activity. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1018316
American Medical Association (AMA)
Del-Toro-Sánchez, Carmen Lizette& Bautista-Bautista, Nereyda& Blasco-Cabal, José Luis& Gonzalez-Ávila, Marisela& Gutiérrez-Lomelí, Melesio& Arriaga-Alba, Myriam. Antimutagenicity of Methanolic Extracts from Anemopsis californica in Relation to Their Antioxidant Activity. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1018316
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018316