Effect of the Herbal Drug Guilu Erxian Jiao on Muscle Strength, Articular Pain, and Disability in Elderly Men with Knee Osteoarthritis
Joint Authors
Chen, Der-Yuan
Tsai, Chen-Chen
Chou, Yin-Yi
Chen, Yi-Ming
Tang, Yih-Jing
Ho, Hui-Ching
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-16
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Guilu Erxian Jiao (GEJ) is a widely used Chinese herbal remedy for knee osteoarthritis, but its clinical efficacy is unknown.
Methods.
We enrolled 42 elderly male patients with knee OA, including 21 patients who received the herbal drug GEJ as the case group and 21 patients who did not receive GEJ as the control group.
The effects of 12 weeks of GEJ treatment on muscle strength of lower limbs were measured by a Biodex dynamometer, with disability evaluated on the Lequesne index and articular pain measured on the visual analog scale (VAS) between the two groups on the baseline and after treatment.
Results.
There were significant increases in the levels of muscle strength of TQ/BW-ext-dominant and TQ/BW-flex-dominant between the two groups after treatment ( P < 0.05 ).
There were also significant increases in muscle strength of knee extensor muscles in the GEJ-treated group ( n = 21 ) self-controlled before and after 12 weeks of treatment (all P < 0.01 ).
There were significant decreases in articular pain ( P < 0.01 ) and Lequesne index scores ( P < 0.01 ) in the GEJ-treated group when compared to the non-GEJ-treated group.
Conclusions.
Our results showed that GEJ is effective and is tolerated well in elderly men with knee OA.
American Psychological Association (APA)
Tsai, Chen-Chen& Chou, Yin-Yi& Chen, Yi-Ming& Tang, Yih-Jing& Ho, Hui-Ching& Chen, Der-Yuan. 2014. Effect of the Herbal Drug Guilu Erxian Jiao on Muscle Strength, Articular Pain, and Disability in Elderly Men with Knee Osteoarthritis. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1018350
Modern Language Association (MLA)
Tsai, Chen-Chen…[et al.]. Effect of the Herbal Drug Guilu Erxian Jiao on Muscle Strength, Articular Pain, and Disability in Elderly Men with Knee Osteoarthritis. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1018350
American Medical Association (AMA)
Tsai, Chen-Chen& Chou, Yin-Yi& Chen, Yi-Ming& Tang, Yih-Jing& Ho, Hui-Ching& Chen, Der-Yuan. Effect of the Herbal Drug Guilu Erxian Jiao on Muscle Strength, Articular Pain, and Disability in Elderly Men with Knee Osteoarthritis. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1018350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018350