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Antifungal and Antioxidant Activities of the Essential Oil from Angelica koreana Nakai
Joint Authors
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
The purpose of this study is to determine the antifungal and antioxidant activities of the essential oil from Angelica koreana.
Methods.
Essential oil was obtained from the dried roots of A.
koreana by steam distillation, and its composition was identified by gas chromatography and mass spectrometry (GC-MS).
The minimal inhibitory concentrations (MICs) of the oil fraction and its main components were determined by broth dilution assay using common pathogenic Aspergillus and Trichophyton species.
The combined effects of the oils with itraconazole were evaluated using a checkerboard titer test.
In addition, 1,1-diphenyl-2-picryl-hydrazil (DPPH) free radical scavenging, nitrite inhibition, and reducing power were determined to assess the antioxidant activity of this oil.
Results.
The essential oil fraction and its main components showed inhibitory activity against all of the tested fungi, with minimal inhibitory concentrations (MICs) of 250–1000 μg/mL.
Furthermore, this oil exhibited synergism when combined with itraconazole.
Conclusion.
In the treatment of infections caused by Aspergillus and Trichophyton species, combining itraconazole with either A.
koreana essential oil or its main components may reduce the minimum effective dose of itraconazole required and, thus, minimize its side effects.
In addition, this oil is a promising source of natural antioxidant agents.
American Psychological Association (APA)
Roh, Junghyun& Shin, Seungwon. 2014. Antifungal and Antioxidant Activities of the Essential Oil from Angelica koreana Nakai. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1018438
Modern Language Association (MLA)
Roh, Junghyun& Shin, Seungwon. Antifungal and Antioxidant Activities of the Essential Oil from Angelica koreana Nakai. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1018438
American Medical Association (AMA)
Roh, Junghyun& Shin, Seungwon. Antifungal and Antioxidant Activities of the Essential Oil from Angelica koreana Nakai. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1018438
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018438