Lipid Lowering Effect of Punica granatum L. Peel in High Lipid Diet Fed Male Rats
Joint Authors
Sadeghipour, Alireza
Eidi, Maryam
Ilchizadeh Kavgani, Ali
Ghahramani, Reza
Shahabzadeh, Saleh
Anissian, Ali
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Many herbal medicines have been recommended for the treatment of dyslipidemia.
The antilipidemic effect of hydroethanolic extract of pomegranate peel (Punica granatum L.) was investigated in high lipid diet fed male rats.
Intraperitoneally administration of pomegranate peel extract (50, 100, 200, and 300 mg/kg body weight) for 23 days on the levels of serum cholesterol, triglycerides, LDL, HDL, alkaline phosphatase (AP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in high lipid diet fed male rats was evaluated.
Treatment of pomegranate extract decreased body weight in treated rats, significantly.
Administration of the plant extract significantly decreased serum total cholesterol, triglycerides, LDL-C, alkaline phosphatise, AST, and ALT levels, whereas it increased serum HDL-C in high lipid diet fed rats in comparison to saline control group.
Also, histopathological study showed that treatment of pomegranate peel extract attenuates liver damage in high lipid diet fed rats in comparison to saline group.
It is concluded that the plant should be considered as an excellent candidate for future studies on dyslipidemia.
American Psychological Association (APA)
Sadeghipour, Alireza& Eidi, Maryam& Ilchizadeh Kavgani, Ali& Ghahramani, Reza& Shahabzadeh, Saleh& Anissian, Ali. 2014. Lipid Lowering Effect of Punica granatum L. Peel in High Lipid Diet Fed Male Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1018469
Modern Language Association (MLA)
Sadeghipour, Alireza…[et al.]. Lipid Lowering Effect of Punica granatum L. Peel in High Lipid Diet Fed Male Rats. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1018469
American Medical Association (AMA)
Sadeghipour, Alireza& Eidi, Maryam& Ilchizadeh Kavgani, Ali& Ghahramani, Reza& Shahabzadeh, Saleh& Anissian, Ali. Lipid Lowering Effect of Punica granatum L. Peel in High Lipid Diet Fed Male Rats. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1018469
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018469