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Moxibustion Activates Macrophage Autophagy and Protects Experimental Mice against Bacterial Infection
Joint Authors
Li, Xiaojuan
Guo, Guanhua
Shen, Feng
Kong, Lihong
Liang, Fengxia
Sun, Guojie
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Moxibustion is one of main therapies in traditional Chinese medicine and uses heat stimulation on the body surface from the burning of moxa to release pain or treat diseases.
Emerging studies have shown that moxibustion can generate therapeutic effects by activating a series of signaling pathways and neuroendocrine-immune activities.
Here we show moxibustion promoted profound macrophage autophagy in experimental Kunming mice, with reduced Akt phosphorylation and activated eIF2α phosphorylation.
Consequently, moxibustion promoted bacterial clearance by macrophages and protected mice from mortality due to bacterial infection.
These results indicate that moxibustion generates a protective response by activating autophagy against bacterial infections.
American Psychological Association (APA)
Li, Xiaojuan& Guo, Guanhua& Shen, Feng& Kong, Lihong& Liang, Fengxia& Sun, Guojie. 2014. Moxibustion Activates Macrophage Autophagy and Protects Experimental Mice against Bacterial Infection. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1018484
Modern Language Association (MLA)
Li, Xiaojuan…[et al.]. Moxibustion Activates Macrophage Autophagy and Protects Experimental Mice against Bacterial Infection. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1018484
American Medical Association (AMA)
Li, Xiaojuan& Guo, Guanhua& Shen, Feng& Kong, Lihong& Liang, Fengxia& Sun, Guojie. Moxibustion Activates Macrophage Autophagy and Protects Experimental Mice against Bacterial Infection. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1018484
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018484