Synthesis of new oxazepine and thaizolidine compounds derived from pyrimidine-2(2h)-one
Other Title(s)
تحضير مركبات أوكسازبين و ثايازولدين جديدة مشتقة من مركبات بيريميدين-2(2H)- اون
Joint Authors
Ahmad, Natiq Ghanim
Sulayman, Zaynab Hasan
Source
al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah
Issue
Vol. 29, Issue 2 (30 Jun. 2020), pp.186-200, 15 p.
Publisher
University of Mosul College of Education for Pure Science
Publication Date
2020-06-30
Country of Publication
Iraq
No. of Pages
15
Main Subjects
Topics
Abstract EN
In this paper the compounds (11-20) (methyl pyrimidine - 2(1H)-one and others phenyl pyrimidine -2(1H)- one) that had been already prepared from α, β unsaturated carbonyl compounds that are called chalcones, these compounds are usually prepared from the reaction of different aldehydes (4-methoxy benzaldehyde, 2-nitro benzaldehyde, 3-nitrobenzaldehyde, 4-N,N—dimethyle amino benzaldehyde, benzaldehyde, 4-nitrobenzaldehyde) with different ketones (acetone, acetophenone, 2-nitro acetophenone, 3- nitro acetophenone) After preparing and purifying them a suitable mesurment for physical, chemical and spectroscopic properties had been made to get chalcones that reacted with urea under known chemical conditions to get the pyrimidinone compounds that we need.
Pyrimidine compounds had been reacted with two aromatic amines (2,4- dinitro aniline and 4- amino acetophenone) using glacial acetic acid as catalyst in absolute ethanol giving a new compounds of schiff's bases (21-40).
New thiazolidine 4-one (41-50) had been synthesized from the reacting of Schiff's bases (21-30) with thioglycolic acid in absolute ethanol.
1,3- oxazepine derivatives.
(51-60) had been prepared from reaction between Schiff's bases (31-40) and malic anhydrid in absolut ethanol.
The structures of the Synthesized compounds had been estimated by IR, 1HNMR and some physical data.
American Psychological Association (APA)
Sulayman, Zaynab Hasan& Ahmad, Natiq Ghanim. 2020. Synthesis of new oxazepine and thaizolidine compounds derived from pyrimidine-2(2h)-one. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah،Vol. 29, no. 2, pp.186-200.
https://search.emarefa.net/detail/BIM-1018706
Modern Language Association (MLA)
Sulayman, Zaynab Hasan& Ahmad, Natiq Ghanim. Synthesis of new oxazepine and thaizolidine compounds derived from pyrimidine-2(2h)-one. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah Vol. 29, no. 2 (2020), pp.186-200.
https://search.emarefa.net/detail/BIM-1018706
American Medical Association (AMA)
Sulayman, Zaynab Hasan& Ahmad, Natiq Ghanim. Synthesis of new oxazepine and thaizolidine compounds derived from pyrimidine-2(2h)-one. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah. 2020. Vol. 29, no. 2, pp.186-200.
https://search.emarefa.net/detail/BIM-1018706
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 199-200
Record ID
BIM-1018706