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Irritant Contact Dermatitis Risk of Common Topical Traditional Chinese Medicines Used for Skin-Lightening: A Pilot Clinical Trial with 30 Volunteers
Joint Authors
Chen, Huey-Yi
Chen, Wen-Chi
Tsai, Kao-Sung
Lin, Tzu-Chun
Wu, Meng-Tse
Shen, Jui-Lung
Jan, Chia-Ing
Chen, Yung-Hsiang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Topical traditional Chinese medicine- (TTCM-) related contact dermatitis is not uncommon but ignored.
Patch and photopatch tests using 6 individual herbal ingredients and Bai-Zhi-Kao (BZK; 白 芷 膏), a skin-lightening TTCM preparation, were conducted on 30 participants.
Twenty-five subjects showed at least 1 positive reaction, including 6 (20.0%) participants who reacted to BZK.
The majority reacted to Radix Ampelopsis japonica (Bai-Lian; 白 蘞) (60.0%), whereas few reacted to Rhizoma Bletilla striata (Bai-Ji; 白 芨) (16.7%), Rhizoma Atractylodis macrocephalae (Bai-Zhu; 白 朮) (10.0%), Radix Angelicae dahuricae (Bai-Zhi; 白 芷) (3.3%), and Herba asari (Xi-Xin; 細 辛) (3.3%).
In the photopatch test, 3 participants (10.0%) reacted positively to BZK and 10 to ≥1 constituent; however, all reacted to Radix Angelicae dahuricae (26.7%), Radix Ampelopsis japonica (13.3%), and Rhizoma Bletilla striata (3.3%).
In contrast, no subjects showed positive reactions to Sclerotium Poria cocos (Bai-Fu-Ling; 白 茯 苓).
Thus, BZK and its constituents might present potential latent risk of contact dermatitis owing to the possible presence of Radix Ampelopsis japonica and Radix Angelicae dahuricae.
Furthermore, TTCMs, particularly cosmetic products, must be used carefully, with ample warning of potential contact dermatitis risk.
American Psychological Association (APA)
Tsai, Kao-Sung& Lin, Tzu-Chun& Wu, Meng-Tse& Shen, Jui-Lung& Jan, Chia-Ing& Chen, Huey-Yi…[et al.]. 2014. Irritant Contact Dermatitis Risk of Common Topical Traditional Chinese Medicines Used for Skin-Lightening: A Pilot Clinical Trial with 30 Volunteers. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1018735
Modern Language Association (MLA)
Tsai, Kao-Sung…[et al.]. Irritant Contact Dermatitis Risk of Common Topical Traditional Chinese Medicines Used for Skin-Lightening: A Pilot Clinical Trial with 30 Volunteers. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1018735
American Medical Association (AMA)
Tsai, Kao-Sung& Lin, Tzu-Chun& Wu, Meng-Tse& Shen, Jui-Lung& Jan, Chia-Ing& Chen, Huey-Yi…[et al.]. Irritant Contact Dermatitis Risk of Common Topical Traditional Chinese Medicines Used for Skin-Lightening: A Pilot Clinical Trial with 30 Volunteers. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1018735
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018735