The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice
Joint Authors
Ma, Xiaojuan
Ma, Xiumin
Ma, Zhixing
Sun, Zhan
Yu, Wenyan
Wang, Jing
Li, Fengsen
Ding, Jianbing
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
It has been proved that Uygur herb Hyssopus offcinalis L.
could affect the levels of some cytokines (such as IL-4, IL-6, IL-17, and IFN-γ) in asthmatic mice.
By detection of the expressions of MMP-9 and TIMP-1 and the morphological changes, the aim of this research is to reveal the mechanism of Uygur herb Hyssopus offcinalis L.
in the process of airway remodeling.
It was observed that the expressions of MMP-9 and TIMP-1 increased, but the ratio of MMP-9/TIMP-1 decreased in airway remodeling group.
However, the expression of both MMP-9 and TIMP-1 decreased after being treated with dexamethasone and Hyssopus offcinalis L., accompanied by the relieved pathological changes, including collagen deposition, mucus secretion, and smooth muscle proliferation.
It is suggested that Uygur herb Hyssopus offcinalis L.
could inhibit airway remodeling by correcting imbalance of MMP-9/TIMP-1 ratio.
American Psychological Association (APA)
Ma, Xiaojuan& Ma, Xiumin& Ma, Zhixing& Sun, Zhan& Yu, Wenyan& Wang, Jing…[et al.]. 2014. The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1018931
Modern Language Association (MLA)
Ma, Xiaojuan…[et al.]. The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1018931
American Medical Association (AMA)
Ma, Xiaojuan& Ma, Xiumin& Ma, Zhixing& Sun, Zhan& Yu, Wenyan& Wang, Jing…[et al.]. The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1018931
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1018931
