![](/images/graphics-bg.png)
Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats
Joint Authors
Diao, Bao-zhong
Jin, Wei-rong
Yu, Xue-jing
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The present study aimed to evaluate the therapeutic effects of polysaccharides from Inonotus obliquus (PIO) on streptozotocin- (STZ-) induced diabetic symptoms and their potential mechanisms.
The effect of PIO on body weight, blood glucose, damaged pancreatic β -cells, oxidative stresses, proinflammatory cytokines, and glucose metabolizing enzymes in liver was studied.
The results show that administration of PIO can restore abnormal oxidative indices near normal levels.
The STZ-damaged pancreatic β -cells of the rats were partly recovered gradually after the mice were administered with PIO 6 weeks later.
Therefore, we may assume that PIO is effective in the protection of STZ-induced diabetic rats and PIO may be of use as antihyperglycemic agent.
American Psychological Association (APA)
Diao, Bao-zhong& Jin, Wei-rong& Yu, Xue-jing. 2014. Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1020323
Modern Language Association (MLA)
Diao, Bao-zhong…[et al.]. Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1020323
American Medical Association (AMA)
Diao, Bao-zhong& Jin, Wei-rong& Yu, Xue-jing. Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1020323
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1020323