Effect of fennel and dill seeds on serum lipid profiles of rats feeding high fat diet

Other Title(s)

تأثير بذور الشمر و الشبت علي صورة دهون سيرم الدم في الفئران التي يتم تغذيتها على وجبات عالية الدهون

Joint Authors

Rifat, Wafa'a Ahmad
al-Nassag, Dua'a al-Sayid

Source

مجلة البحوث في مجالات التربية النوعية : مجلة علمية محكمة

Publisher

Minia University Faculty of Specific Education

Publication Date

2019-05-31

Country of Publication

Egypt

No. of Pages

21

Main Subjects

Botany
Veterinary Medicine

Topics

• Mice
• Foeniculum
• Dill

English Abstract

D ill and fennel seeds are herbal plants cultivated in various regions worldwide; they have many therapeutic effects such as anti-inflammatory, antibacterial, antiviral, anti-hyperlipidemia and antidiabetic.

Therefore, this study was conducted to examine the effect of fennel and dill seeds powder on serum lipid profile of rats feeding high fat diet.

Forty adult male albino rats weighting (200 ±7g) were divided into eight equal groups of 5 animals each, one was kept as a control (-Ve) group, while the other 7 groups were fed on high fat diet (HFD), group (2) were left as a control (+Ve) fed on HFD only all experiment period (28 days), groups (3,4) fed on HFD+ 2.5% and 5% of dill seeds, respectively, while groups (5,6) fed on HFD+ 2.5% and 5% of fennel seeds, respectively, the last groups (7,8) fed on dill and fennel seeds mix (50/50 w/w) with 2.5% and 5%, respectively.

At the end of experiment serum glucose level, liver enzymes activities, kidney functions and lipid profile were examined.

The results indicated that the increase of fennel seeds or dill seeds concentration resulted in reduction of serum glucose level and significant (p≤0.05) decreased serum very low-density lipoprotein (VLDL), low density lipoprotein (LDL), triglyceride and cholesterol.

Also, the results revealed that fennel seeds have a better effect than dill seeds on high density lipoprotein (HDL) level.

Treatment with fennel seeds or dill seeds at different levels caused significant (p≤0.05) decreased uric acid, creatinine and urea levels compared to positive control group.

The results also revealed there no significant differences between the groups in albumin level.

There was a significant (p≤0.05) decrease in the activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) of fennel seeds and dill seeds groups compared to positive control group.

Therefore, the present study concluded that fennel and dill seeds powder could be used into daily foods and beverages as hypo-lipidemic herbs.

Data Type

Conference Papers

Record ID

BIM-1020628

• APA
• MLA
• AMA