Alternative Splicing of Transcription Factors' Genes: Beyond the Increase of Proteome Diversity
Joint Authors
Talavera, David
de la Cruz, Xavier
Orozco, Modesto
Source
International Journal of Genomics
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-06-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Functional modification of transcription regulators may lead to developmental changes and phenotypical differences between species.
In this work, we study the influence of alternative splicing on transcription factors in human and mouse.
Our results show that the impact of alternative splicing on transcription factors is similar in both species, meaning that the ways to increase variability should also be similar.
However, when looking at the expression patterns of transcription factors, we observe that they tend to diverge regardless of the role of alternative splicing.
Finally, we hypothesise that transcription regulation of alternatively spliced transcription factors could play an important role in the phenotypical differences between species, without discarding other phenomena or functional families.
American Psychological Association (APA)
Talavera, David& Orozco, Modesto& de la Cruz, Xavier. 2009. Alternative Splicing of Transcription Factors' Genes: Beyond the Increase of Proteome Diversity. International Journal of Genomics،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-1027119
Modern Language Association (MLA)
Talavera, David…[et al.]. Alternative Splicing of Transcription Factors' Genes: Beyond the Increase of Proteome Diversity. International Journal of Genomics No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-1027119
American Medical Association (AMA)
Talavera, David& Orozco, Modesto& de la Cruz, Xavier. Alternative Splicing of Transcription Factors' Genes: Beyond the Increase of Proteome Diversity. International Journal of Genomics. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-1027119
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1027119