Leiomyosarcomas of Vascular Origin in the Extremity
Joint Authors
Carter, Simon R.
Abudu, Adesegun
Abed, R.
Grimer, Robert
Tillman, Roger M.
Jeys, L. M.
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-06-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Between 1996 and 2006 a total of 278 patients with soft tissue Leiomyosarcoma were treated at our centre.
We identified 16 patients (5.8%) where the tumour directly arose from the blood vessels.
These tumours were studied to determine their prognosis and behaviour.
All tumors were in the lower limbs: 11 from the femoral vein, 3 popliteal vein, and 2 from the posterior tibial vein.
Mean tumour size was 10.4 cm (3 to 33).
Histological grade was high in all patients.
Surgical treatment was amputation in one, excision with or without vascular reconstruction in 12 followed by radiotherapy, and 3 patients had no surgery because of advanced disease at diagnosis.
Seven out of the 16 patients (44%) had metastasis at diagnosis, and five patients withoutmetastasis at diagnosis rapidly developed metastases at a median time of 5 months from diagnosis (2–30 months).
The overallsurvival of the patients at 5 years was 25% which was considerably worse than those with nonvascular leiomyosarcoma.
Weconclude that patients with leiomyosarcoma of vascular origin have a very high risk of metastases and poor prognosis when treated inthe conventional way.
American Psychological Association (APA)
Abed, R.& Abudu, Adesegun& Grimer, Robert& Tillman, Roger M.& Carter, Simon R.& Jeys, L. M.. 2009. Leiomyosarcomas of Vascular Origin in the Extremity. Complexity،Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-1027129
Modern Language Association (MLA)
Abed, R.…[et al.]. Leiomyosarcomas of Vascular Origin in the Extremity. Complexity No. 2009 (2009), pp.1-4.
https://search.emarefa.net/detail/BIM-1027129
American Medical Association (AMA)
Abed, R.& Abudu, Adesegun& Grimer, Robert& Tillman, Roger M.& Carter, Simon R.& Jeys, L. M.. Leiomyosarcomas of Vascular Origin in the Extremity. Complexity. 2009. Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-1027129
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1027129