Anti-Inflammatory Effects of Inonotus obliquus in Colitis Induced by Dextran Sodium Sulfate
Joint Authors
Jeon, Yun Hui
An, Chi Sun
Hur, Sun Jin
Bak, Jong Phil
Jeoung, Young Jun
Choi, Se Young
Lim, Beong Ou
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2009), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A total of 28 male BALB/c mice (average weight 20.7 ± 1.6 g) were divided into 4 treatment groups and fed a commercial diet (A), a commercial diet + induced colitis by dextran sodium sulfate (DSS) (B), Inonotus obliquus (IO) administration (C), and IO administration + induced colitis by DSS (D).
IO treatment (C, D) decreased the expression of tumor necrosis factor (TNF)-α and signal transducers and activators of transcription (STAT)1 compared to those of the colitis induced group (B).
The expressions of IL-4 and STAT6 were decreased in group D compared to the colitis induced group (B).
The serum immunoglobulin (Ig)E level decreased in IO treatment groups (C, D) compared to no IO treatment groups (A and B) although there was no significant difference between the IO treatment groups.
Extract from IO itself had a weak cytotoxic effect on murine macrophage cell line (RAW264.7 cells).
Extract from IO inhibited lipopolysaccharide- (LPS-) induced, TNF-α, STAT1, pSTAT1, STAT6, and pSTAT6 production in RAW264.7 cells.
American Psychological Association (APA)
Choi, Se Young& Hur, Sun Jin& An, Chi Sun& Jeon, Yun Hui& Jeoung, Young Jun& Bak, Jong Phil…[et al.]. 2010. Anti-Inflammatory Effects of Inonotus obliquus in Colitis Induced by Dextran Sodium Sulfate. BioMed Research International،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-1027158
Modern Language Association (MLA)
Choi, Se Young…[et al.]. Anti-Inflammatory Effects of Inonotus obliquus in Colitis Induced by Dextran Sodium Sulfate. BioMed Research International No. 2010 (Dec. 2010), pp.1-5.
https://search.emarefa.net/detail/BIM-1027158
American Medical Association (AMA)
Choi, Se Young& Hur, Sun Jin& An, Chi Sun& Jeon, Yun Hui& Jeoung, Young Jun& Bak, Jong Phil…[et al.]. Anti-Inflammatory Effects of Inonotus obliquus in Colitis Induced by Dextran Sodium Sulfate. BioMed Research International. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-1027158
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1027158