Planar Cell Polarity Signaling Pathway in Congenital Heart Diseases
Joint Authors
Mu, Dezhi
Wu, Gang
Ge, Jiao
Huang, Xupei
Hua, Yimin
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Congenital heart disease (CHD) is a common cardiac disorder in humans.
Despite many advances in the understanding of CHD and the identification of many associated genes, the fundamental etiology for the majority of cases remains unclear.
The planar cell polarity (PCP) signaling pathway, responsible for tissue polarity in Drosophila and gastrulation movements and cardiogenesis in vertebrates, has been shown to play multiple roles during cardiac differentiation and development.
The disrupted function of PCP signaling is connected to some CHDs.
Here, we summarize our current understanding of how PCP factors affect the pathogenesis of CHD.
American Psychological Association (APA)
Wu, Gang& Ge, Jiao& Huang, Xupei& Hua, Yimin& Mu, Dezhi. 2011. Planar Cell Polarity Signaling Pathway in Congenital Heart Diseases. BioMed Research International،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-1027621
Modern Language Association (MLA)
Wu, Gang…[et al.]. Planar Cell Polarity Signaling Pathway in Congenital Heart Diseases. BioMed Research International No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-1027621
American Medical Association (AMA)
Wu, Gang& Ge, Jiao& Huang, Xupei& Hua, Yimin& Mu, Dezhi. Planar Cell Polarity Signaling Pathway in Congenital Heart Diseases. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-1027621
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1027621