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Profiles of Biomarkers of Excess Alcohol Consumption in Patients Undergoing Total Hip Replacement: Correlation with Function
Joint Authors
Huntley, James
Robertson, Francis P. C.
Howie, Colin R.
Jenkins, P.
Duckworth, Andrew D.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Aims.
Patients who misuse alcohol may be at increased risk of surgical complications and poorer function following hip replacement.
Identification and intervention may lead to harm reduction and improve the outcomes of surgery.
The aim of this study was to determine the prevalence of biomarker elevation in patients undergoing hip replacement and to investigate any correlation with functional scores and complications.
Methods.
We performed a retrospective study that examined the profile of biomarkers of alcohol misuse in 1049 patients undergoing hip replacement.
Results.
Gamma-glutamyltransferase was elevated in 150 (17.6%), and mean corpuscular volume was elevated in 23 (4%).
At one year general physical health was poorer where there was elevation of γGT, and the mental health and hip function was poorer with elevation of MCV.
There were no differences in complications.
Discussion.
Raised biomarkers can alert clinicians to potential problems.
They also provide an opportunity to perform further investigation and offer intervention.
Future research should focus on the use in orthopaedic practice of validated screening questionnaires and more sensitive biomarkers of alcohol misuse.
Conclusion.
This study demonstrates a potential substantial proportion of unrecognised alcohol misuse that is associated with poorer functional scores in patients after total hip replacement.
American Psychological Association (APA)
Jenkins, P.& Duckworth, Andrew D.& Robertson, Francis P. C.& Howie, Colin R.& Huntley, James. 2011. Profiles of Biomarkers of Excess Alcohol Consumption in Patients Undergoing Total Hip Replacement: Correlation with Function. The Scientific World Journal،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-1027870
Modern Language Association (MLA)
Jenkins, P.…[et al.]. Profiles of Biomarkers of Excess Alcohol Consumption in Patients Undergoing Total Hip Replacement: Correlation with Function. The Scientific World Journal No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-1027870
American Medical Association (AMA)
Jenkins, P.& Duckworth, Andrew D.& Robertson, Francis P. C.& Howie, Colin R.& Huntley, James. Profiles of Biomarkers of Excess Alcohol Consumption in Patients Undergoing Total Hip Replacement: Correlation with Function. The Scientific World Journal. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-1027870
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1027870