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Inhibition of Staphylococcus epidermidis Biofilm Formation by Traditional Thai Herbal Recipes Used for Wound Treatment
Joint Authors
Voravuthikunchai, Supayang Piyawan
Sompetch, K.
Mukdee, S.
Jansrisewangwong, S.
Srichai, T.
Maneenoon, K.
Limsuwan, S.
Chusri, Sasitorn
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Development of biofilm is a key mechanism involved in Staphylococcus epidermidis virulence during device-associated infections.
We aimed to investigate antibiofilm formation and mature biofilm eradication ability of ethanol and water extracts of Thai traditional herbal recipes including THR-SK004, THR-SK010, and THR-SK011 against S.
epidermidis.
A biofilm forming reference strain, S.
epidermidis ATCC 35984 was employed as a model for searching anti-biofilm agents by MTT reduction assay.
The results revealed that the ethanol extract of THR-SK004 (THR-SK004E) could inhibit the formation of S.
epidermidis biofilm on polystyrene surfaces.
Furthermore, treatments with the extract efficiently inhibit the biofilm formation of the pathogen on glass surfaces determined by scanning electron microscopy and crystal violet staining.
In addition, THR-SK010 ethanol extract (THR-SK010E; 0.63–5 μg/mL) could decrease 30 to 40% of the biofilm development.
Almost 90% of a 7-day-old staphylococcal biofilm was destroyed after treatment with THR-SK004E (250 and 500 μg/mL) and THR-SK010E (10 and 20 μg/mL) for 24 h.
Therefore, our results clearly demonstrated THR-SK004E could prevent the staphylococcal biofilm development, whereas both THR-SK004E and THR-SK010E possessed remarkable eradication ability on the mature staphylococcal biofilm.
American Psychological Association (APA)
Chusri, Sasitorn& Sompetch, K.& Mukdee, S.& Jansrisewangwong, S.& Srichai, T.& Maneenoon, K.…[et al.]. 2012. Inhibition of Staphylococcus epidermidis Biofilm Formation by Traditional Thai Herbal Recipes Used for Wound Treatment. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028127
Modern Language Association (MLA)
Chusri, Sasitorn…[et al.]. Inhibition of Staphylococcus epidermidis Biofilm Formation by Traditional Thai Herbal Recipes Used for Wound Treatment. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-1028127
American Medical Association (AMA)
Chusri, Sasitorn& Sompetch, K.& Mukdee, S.& Jansrisewangwong, S.& Srichai, T.& Maneenoon, K.…[et al.]. Inhibition of Staphylococcus epidermidis Biofilm Formation by Traditional Thai Herbal Recipes Used for Wound Treatment. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028127
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028127