Effect of a Semisolid Formulation of Linum usitatissimum L. (Linseed) Oil on the Repair of Skin Wounds
Joint Authors
Evêncio, Liriane Baratella
de Medeiros, Paloma Lys
de Aquino, Camila Maria Ferreira
Maia, Maria Bernadete de Sousa
Franco, Eryvelton de Souza
Góes, Alexandre José da Silva
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The purpose of this study was to investigate the effects of a semisolid formulation of linseed oil, SSFLO (1%, 5%, or 10%) or in natura linseed oil on skin wounds of rats.
We used wound models, incisional and excisional, to evaluate, respectively, the contraction/reepithelialization of the wound and resistance to mechanical traction.
The groups (n=6) treated with SSFLO (1% or 5%) began the process of reepithelialization, to a significant extent (P<.05), on the sixth day, when compared to the petroleum jelly control group.
On 14th day for the groups treated with SSFLO (1% or 5%), 100% reepithelialization was found, while in the petroleum jelly control group, this was only 33.33%.
Our study showed that topical administration of SSFLO (1% or 5%) in excisional wounds allowed reepithelialization in 100% of treated animals.
Therefore, a therapeutic potential of linseed oil, when used at low concentrations in the solid pharmaceutical formulations, is suggested for the process of dermal repair.
American Psychological Association (APA)
Franco, Eryvelton de Souza& de Aquino, Camila Maria Ferreira& de Medeiros, Paloma Lys& Evêncio, Liriane Baratella& Góes, Alexandre José da Silva& Maia, Maria Bernadete de Sousa. 2011. Effect of a Semisolid Formulation of Linum usitatissimum L. (Linseed) Oil on the Repair of Skin Wounds. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028208
Modern Language Association (MLA)
Franco, Eryvelton de Souza…[et al.]. Effect of a Semisolid Formulation of Linum usitatissimum L. (Linseed) Oil on the Repair of Skin Wounds. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1028208
American Medical Association (AMA)
Franco, Eryvelton de Souza& de Aquino, Camila Maria Ferreira& de Medeiros, Paloma Lys& Evêncio, Liriane Baratella& Góes, Alexandre José da Silva& Maia, Maria Bernadete de Sousa. Effect of a Semisolid Formulation of Linum usitatissimum L. (Linseed) Oil on the Repair of Skin Wounds. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028208
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028208