Repurposing of Yunnan Baiyao as an Alternative Therapy for Minor Recurrent Aphthous Stomatitis
Joint Authors
Yan, Zhimin
Hua, Hong
Liu, Xiaosong
Guan, Xiaobing
Chen, Ruiyang
Liu, Yang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The study was designed to evaluate the efficacy and safety of an herbal extract of Yunnan Baiyao formulated in toothpaste as an alternative therapy for minor RAS.
A randomized, double-blind, placebo-controlled clinical trial (from March 2010 to March 2011) was conducted on a cohort of 227 minor RAS patients.
The toothpaste containing Yunnan Baiyao was used twice daily as part of the patient's routine oral hygiene for 5 days.
An assessment of ulcerative size and pain was recorded on day 0 (baseline), day 3, and day 5.
Any noted adverse reactions were recorded.
All data were analyzed using the SAS software 8.0.
As a result, the toothpaste containing Yunnan Baiyao began to present noticeable effectiveness on ulcer healing (ulcer size) by day 3 (27.5% versus 15.8%, P<0.05), which further improved by day 5 when compared to the placebo (66.4% versus 50.0%, P=0.01).
A significant difference in alleviating pain was noted on day 5 for those who used the toothpaste containing Yunnan Baiyao (66.4% versus 51.8%, P<0.05).
No side effects were noted as a result of the Yunnan Baiyao.
Therefore, Yunnan Baiyao may provide an alternative therapy for minor ulcers by promoting healing.
American Psychological Association (APA)
Liu, Xiaosong& Guan, Xiaobing& Chen, Ruiyang& Hua, Hong& Liu, Yang& Yan, Zhimin. 2012. Repurposing of Yunnan Baiyao as an Alternative Therapy for Minor Recurrent Aphthous Stomatitis. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028231
Modern Language Association (MLA)
Liu, Xiaosong…[et al.]. Repurposing of Yunnan Baiyao as an Alternative Therapy for Minor Recurrent Aphthous Stomatitis. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1028231
American Medical Association (AMA)
Liu, Xiaosong& Guan, Xiaobing& Chen, Ruiyang& Hua, Hong& Liu, Yang& Yan, Zhimin. Repurposing of Yunnan Baiyao as an Alternative Therapy for Minor Recurrent Aphthous Stomatitis. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028231
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028231