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Pilot Study with regard to the Wound Healing Activity of Protein from Calotropis procera (Ait.) R. Br.
Joint Authors
Perumal Samy, Ramar
Chow, Vincent T. K.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-29
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
We provide the scientific basis for the use of Calotropis procera for treating skinand wound infections in traditional medicine.
The aqueous extract of stem-bark of C.
procera exhibited more pronounced potent antimicrobial activity.
Calo-protein was purified and identified from the most-active aqueous extracts of C.
procera and showed broad-spectrum activity.
Calo-protein inhibited the growth of S.
aureus and E.
aerogenes effectively at 25 μg/ml concentration.
Mice topically treated with Calo-protein revealed significant wound healing after 14 days comparable to fusidic acid (FA) as positive control.
This protein was devoid of cytolytic effect even at higher concentrations on skin cells after 24 h.
Further investigation of this Calo-protein of C.
procera on bacterial inhibition may provide a better understanding of the scientific basis and justification for its use in traditional medicine.
American Psychological Association (APA)
Perumal Samy, Ramar& Chow, Vincent T. K.. 2012. Pilot Study with regard to the Wound Healing Activity of Protein from Calotropis procera (Ait.) R. Br.. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1028236
Modern Language Association (MLA)
Perumal Samy, Ramar& Chow, Vincent T. K.. Pilot Study with regard to the Wound Healing Activity of Protein from Calotropis procera (Ait.) R. Br.. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-1028236
American Medical Association (AMA)
Perumal Samy, Ramar& Chow, Vincent T. K.. Pilot Study with regard to the Wound Healing Activity of Protein from Calotropis procera (Ait.) R. Br.. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1028236
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028236