Antitumor Activities of Kushen: Literature Review
Joint Authors
Hu, Yi-Yang
Xu, Lie-Ming
Sun, Lin
Dong, Shu
Bian, Yanqin
Han, Jun
Zhang, Lijun
Ren, Shuang
Sun, Ming-yu
Liu, Ping
Cao, Hong-yan
Liu, Chenghai
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
To discover and develop novel natural compounds with therapeutic selectivity or that can preferentially kill cancer cells without significant toxicity to normal cells is an important area in cancer chemotherapy.
Kushen, the dried roots of Sophora flavescens Aiton, has a long history of use in traditional Chinese medicine to treat inflammatory diseases and cancer.
Kushen alkaloids (KS-As) and kushen flavonoids (KS-Fs) are well-characterized components in kushen.
KS-As containing oxymatrine, matrine, and total alkaloids have been developed in China as anticancer drugs.
More potent antitumor activities were identified in KS-Fs than in KS-As in vitro and in vivo.
KS-Fs may be developed as novel antitumor agents.
American Psychological Association (APA)
Sun, Ming-yu& Cao, Hong-yan& Sun, Lin& Dong, Shu& Bian, Yanqin& Han, Jun…[et al.]. 2012. Antitumor Activities of Kushen: Literature Review. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1028278
Modern Language Association (MLA)
Sun, Ming-yu…[et al.]. Antitumor Activities of Kushen: Literature Review. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-1028278
American Medical Association (AMA)
Sun, Ming-yu& Cao, Hong-yan& Sun, Lin& Dong, Shu& Bian, Yanqin& Han, Jun…[et al.]. Antitumor Activities of Kushen: Literature Review. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1028278
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028278