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Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil
Joint Authors
Lino Junior, Ruy de Souza
Parente, Leila Maria Leal
Tresvenzol, Leonice Manrique Faustino
Vinaud, Marina Clare
de Paula, José Realino
Paulo, Neusa Margarida
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Calendula officinalis is an annual herb from Mediterranean origin which is popularly used in wound healing and as an anti-inflammatory agent.
In this study, the ethanolic extract, the dichloromethane, and hexanic fractions of the flowers from plants growing in Brazil were produced.
The angiogenic activity of the extract and fractions was evaluated through the chorioallantoic membrane and cutaneous wounds in rat models.
The healing activity of the extract was evaluated by the same cutaneous wounds model through macroscopic, morphometric, histopathologic, and immunohistochemical analysis.
The antibacterial activity of the extract and fractions was also evaluated.
This experimental study revealed that C.
officinalis presented anti-inflammatory and antibacterial activities as well as angiogenic and fibroplastic properties acting in a positive way on the inflammatory and proliferative phases of the healing process.
American Psychological Association (APA)
Parente, Leila Maria Leal& Lino Junior, Ruy de Souza& Tresvenzol, Leonice Manrique Faustino& Vinaud, Marina Clare& de Paula, José Realino& Paulo, Neusa Margarida. 2011. Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028279
Modern Language Association (MLA)
Parente, Leila Maria Leal…[et al.]. Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1028279
American Medical Association (AMA)
Parente, Leila Maria Leal& Lino Junior, Ruy de Souza& Tresvenzol, Leonice Manrique Faustino& Vinaud, Marina Clare& de Paula, José Realino& Paulo, Neusa Margarida. Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028279
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028279