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Systematic Review on the Efficacy and Safety of Herbal Medicines for Vascular Dementia
Joint Authors
Chan, Kam Wa
Li, Min
Man, Sui Cheung
Lu, Jia-Hong
Liu, Liang-Feng
Durairajan, Siva Sundara Kumar
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-20
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Abstract EN
We present a systematic review of existing research that aims to assess the efficacy and safety of herbal medications (HM), as either monotherapy or adjunct to orthodox medications (OM), mainly comprised of cholinesterase inhibitors, for vascular dementia (VaD).
We included 47 studies conducted in mainland China, each testing different HM.
Of 43 HM monotherapy studies, 37 reported HM to be significantly better than OM or placebo; six reported similar efficacy between HM and OM.
All four HM adjuvant studies reported significant efficacy.
No major adverse events for HM were reported.
Heterogeneity in diagnostic criteria, interventions and outcome measures hindered comprehensive data analysis.
Studies suggested that HM can be a safe and effective treatment for VaD, either alone or in conjunction with OM.
However, methodological flaws in the design of the studies limited the extent to which the results could be interpreted.
Thirty most commonly used herbal constituents, including Rhizoma Chuanxiong (Chuanxiong in Chinese), Radix Polygoni Multiflori (Heshouwu in Chinese) and Radix Astragali (Huangqi in Chinese).
were ranked.
Further multi-center trials with large sample sizes, high methodological quality and standardized HM ingredients are necessary for clinical recommendations to be made.
American Psychological Association (APA)
Man, Sui Cheung& Chan, Kam Wa& Lu, Jia-Hong& Durairajan, Siva Sundara Kumar& Liu, Liang-Feng& Li, Min. 2011. Systematic Review on the Efficacy and Safety of Herbal Medicines for Vascular Dementia. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-22.
https://search.emarefa.net/detail/BIM-1028306
Modern Language Association (MLA)
Man, Sui Cheung…[et al.]. Systematic Review on the Efficacy and Safety of Herbal Medicines for Vascular Dementia. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-22.
https://search.emarefa.net/detail/BIM-1028306
American Medical Association (AMA)
Man, Sui Cheung& Chan, Kam Wa& Lu, Jia-Hong& Durairajan, Siva Sundara Kumar& Liu, Liang-Feng& Li, Min. Systematic Review on the Efficacy and Safety of Herbal Medicines for Vascular Dementia. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-22.
https://search.emarefa.net/detail/BIM-1028306
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028306