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Korean Red Ginseng Improves Blood Pressure Stability in Patients with Intradialytic Hypotension
Joint Authors
Hsu, Chung-Hua
Yu, Chun-Chen
Chen, I-Ju
Chang, Ming-Yang
Chiao, Sheng-Lin
Chen, Jiun-Liang
Yang, Sien-Hung
Liu, Ju-Mei
Hung, Cheng-Chieh
Yang, Rong-Chi
Chang, Hui-Chi
Fang, Ji-Tseng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Introduction.
Intradialytic hypotension (IDH) is a common complication during hemodialysis which may increase mortality risks.
Low dose of Korean red ginseng (KRG) has been reported to increase blood pressure.
Whether KRG can improve hemodynamic stability during hemodialysis has not been examined.
Methods.
The 8-week study consisted of two phases: observation phase and active treatment phase.
According to prehemodialysis blood pressure (BP), 38 patients with IDH were divided into group A (BP ≥ 140/90 mmHg, n = 18) and group B (BP < 140/90 mmHg, n = 20).
Patients were instructed to chew 3.5 gm KRG slices at each hemodialysis session during the 4-week treatment phase.
Blood pressure changes, number of sessions disturbed by symptomatic IDH, plasma levels of vasoconstrictors, blood biochemistry, and adverse effects were recorded.
Results.
KRG significantly reduced the degree of blood pressure drop during hemodialysis (P<0.05) and the frequency of symptomatic IDH (P<0.05).
More activation of vasoconstrictors (endothelin-1 and angiotensin II) during hemodialysis was found.
The postdialytic levels of endothelin-1 and angiotensin II increased significantly (P<0.01).
Conclusion.
Chewing KRG renders IDH patients better resistance to acute BP reduction during hemodialysis via activation of vasoconstrictors.
Our results suggest that KRG could be an adjuvant treatment for IDH.
American Psychological Association (APA)
Chen, I-Ju& Chang, Ming-Yang& Chiao, Sheng-Lin& Chen, Jiun-Liang& Yu, Chun-Chen& Yang, Sien-Hung…[et al.]. 2012. Korean Red Ginseng Improves Blood Pressure Stability in Patients with Intradialytic Hypotension. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1028414
Modern Language Association (MLA)
Chen, I-Ju…[et al.]. Korean Red Ginseng Improves Blood Pressure Stability in Patients with Intradialytic Hypotension. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-1028414
American Medical Association (AMA)
Chen, I-Ju& Chang, Ming-Yang& Chiao, Sheng-Lin& Chen, Jiun-Liang& Yu, Chun-Chen& Yang, Sien-Hung…[et al.]. Korean Red Ginseng Improves Blood Pressure Stability in Patients with Intradialytic Hypotension. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1028414
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028414