Antioxidant Activities of Stilbenoids from Rheum emodi Wall

Joint Authors

Chai, Yuan-yuan
Wang, Fang
Li, Yan-li
Xu, Hui
Liu, Ke

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-10-24

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Medicine

Abstract EN

Rheum emodi Wall has been reported to possess protective effect in many inflammatory diseases and oxidative stress-related injuries.

This study aims to investigate antioxidant power of stilbenoids from R.

emodi and then explore the material basis for its antioxidant potential.

The most abundant stilbenoid piceatannol-4′-O-β-D-glucopyranoside (PICG) and its aglycon piceatannol (PICE) were isolated from R.

emodi rhizome.

Using well-accepted antioxidant chemicals as reference, antioxidant activity of these stilbenoids was examined by measuring DPPH and superoxide anion radical scavenging, ferric reducing power, and inhibition of lipid peroxidation in vitro.

Both PICG and PICE displayed promising antioxidant activity in all the four assays.

Comparisons among the tested compounds indicated that PICE has the most potent antioxidant activity and the presence of 3′-hydroxyl group may enhance antioxidant activity of stilbenoids.

The antioxidative effect of PICE at the cellular level was further demonstrated on the model of hydrogen-peroxide-induced H9c2 rat cardiomyoblasts injury.

Taking into account the rapid in vivo metabolic transformation of PICG into PICE it can be inferred that the most abundant stilbenoid PICG may be an important constituent responsible for the antioxidant potential of R.

emodi and promising to be developed as an antioxidant agent for supplementary or therapeutic use.

American Psychological Association (APA)

Chai, Yuan-yuan& Wang, Fang& Li, Yan-li& Liu, Ke& Xu, Hui. 2012. Antioxidant Activities of Stilbenoids from Rheum emodi Wall. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028417

Modern Language Association (MLA)

Chai, Yuan-yuan…[et al.]. Antioxidant Activities of Stilbenoids from Rheum emodi Wall. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1028417

American Medical Association (AMA)

Chai, Yuan-yuan& Wang, Fang& Li, Yan-li& Liu, Ke& Xu, Hui. Antioxidant Activities of Stilbenoids from Rheum emodi Wall. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028417

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1028417