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Ficus deltoidea: A Potential Alternative Medicine for Diabetes Mellitus
Joint Authors
Hamid, Muhajir
Khamis, Shafii
Ismail, Amin
Adam, Zainah
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Ficus deltoidea from the Moraceae family has been scientifically proven to reduce hyperglycemia at different prandial states.
In this study, we evaluate the mechanisms that underlie antihyperglycemic action of Ficus deltoidea.
The results had shown that hot aqueous extract of Ficus deltoidea stimulated insulin secretion significantly with the highest magnitude of stimulation was 7.31-fold (P<0.001).
The insulin secretory actions of the hot aqueous extract involved K+ ATP channel-dependent and K+ ATP-channel-independent pathway.
The extract also has the ability to induce the usage of intracellular Ca2+ to trigger insulin release.
The ethanolic and methanolic extracts enhanced basal and insulin-mediated glucose uptake into adipocytes cells.
The extracts possess either insulin-mimetic or insulin-sensitizing property or combination of both properties during enhancing glucose uptake into such cells.
Meanwhile, the hot aqueous and methanolic extracts augmented basal and insulin-stimulated adiponectin secretion from adipocytes cells.
From this study, it is suggested that Ficus deltoidea has the potential to be developed as future oral antidiabetic agent.
American Psychological Association (APA)
Adam, Zainah& Khamis, Shafii& Ismail, Amin& Hamid, Muhajir. 2012. Ficus deltoidea: A Potential Alternative Medicine for Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1028440
Modern Language Association (MLA)
Adam, Zainah…[et al.]. Ficus deltoidea: A Potential Alternative Medicine for Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-1028440
American Medical Association (AMA)
Adam, Zainah& Khamis, Shafii& Ismail, Amin& Hamid, Muhajir. Ficus deltoidea: A Potential Alternative Medicine for Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1028440
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028440