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Toona sinensis Leaf Aqueous Extract Improves the Functions of Sperm and Testes via Regulating Testicular Proteins in Rats under Oxidative Stress
Joint Authors
Yu, Bu-Chin
Yu, Wen-Jen
Huang, Chun-Yung
Chen, Ying-Hsin
Tsai, Yun-Ching
Chang, Chen-Chin
Chang, Sue-Joan
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Toona sinensis leaf (TSL) is commonly used as a vegetable and in spice in Asia.
In this study, feeding with aqueous extract of TSL (TSL-A) alleviated oxidative stress and recovered the motility and functions of sperm in rats under oxidative stress.
Protein expressions in testes identified by proteomic analysis and verified by Western blot demonstrated that TSL-A not only downregulated the level of glutathione transferase mu6 (antioxidant system), heat shock protein 90 kDa-β (protein misfolding repairing system), cofilin 2 (spermatogenesis), and cyclophilin A (apoptosis) but also upregulated crease3-hydroxy-3-methylglutaryl-coenzyme A synthase 2 (steroidogenesis), heat shock glycoprotein 96, and pancreatic trypsin 1 (sperm-oocyte interaction).
These results indicate that TSL-A promotes the functions of sperm and testes via regulating multiple testicular proteins in rats under oxidative stress, suggesting that TSL-A is a valuable functional food supplement to improve functions of sperm and testes for males under oxidative stress.
American Psychological Association (APA)
Yu, Bu-Chin& Yu, Wen-Jen& Huang, Chun-Yung& Chen, Ying-Hsin& Tsai, Yun-Ching& Chang, Chen-Chin…[et al.]. 2012. Toona sinensis Leaf Aqueous Extract Improves the Functions of Sperm and Testes via Regulating Testicular Proteins in Rats under Oxidative Stress. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1028466
Modern Language Association (MLA)
Yu, Bu-Chin…[et al.]. Toona sinensis Leaf Aqueous Extract Improves the Functions of Sperm and Testes via Regulating Testicular Proteins in Rats under Oxidative Stress. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-1028466
American Medical Association (AMA)
Yu, Bu-Chin& Yu, Wen-Jen& Huang, Chun-Yung& Chen, Ying-Hsin& Tsai, Yun-Ching& Chang, Chen-Chin…[et al.]. Toona sinensis Leaf Aqueous Extract Improves the Functions of Sperm and Testes via Regulating Testicular Proteins in Rats under Oxidative Stress. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1028466
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028466