Traditional Chinese Medicine for Senile Dementia
Joint Authors
Lin, Zhihong
Gu, Jie
Xiu, Jin
Mi, Tingyan
Dong, Jie
Tiwari, Jyoti Kumar
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-25
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Traditional Chinese Medicine (TCM) has a 3000 years' history of human use.
A literature survey addressing traditional evidence from human studies was done, with key result that top 10 TCM herb ingredients including Poria cocos, Radix polygalae, Radix glycyrrhizae, Radix angelica sinensis, and Radix rehmanniae were prioritized for highest potential benefit to dementia intervention, related to the highest frequency of use in 236 formulae collected from 29 ancient Pharmacopoeias, ancient formula books, or historical archives on ancient renowned TCM doctors, over the past 10 centuries.
Based on the history of use, there was strong clinical support that Radix polygalae is memory improving.
Pharmacological investigation also indicated that all the five ingredients mentioned above can elicit memory-improving effects in vivo and in vitro via multiple mechanisms of action, covering estrogen-like, cholinergic, antioxidant, anti-inflammatory, antiapoptotic, neurogenetic, and anti-Aβ activities.
Furthermore, 11 active principles were identified, including sinapic acid, tenuifolin, isoliquiritigenin, liquiritigenin, glabridin, ferulic acid, Z-ligustilide, N-methyl-beta-carboline-3-carboxamide, coniferyl ferulate and 11-angeloylsenkyunolide F, and catalpol.
It can be concluded that TCM has a potential for complementary and alternative role in treating senile dementia.
The scientific evidence is being continuously mined to back up the traditional medical wisdom.
American Psychological Association (APA)
Lin, Zhihong& Gu, Jie& Xiu, Jin& Mi, Tingyan& Dong, Jie& Tiwari, Jyoti Kumar. 2011. Traditional Chinese Medicine for Senile Dementia. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1028473
Modern Language Association (MLA)
Lin, Zhihong…[et al.]. Traditional Chinese Medicine for Senile Dementia. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-1028473
American Medical Association (AMA)
Lin, Zhihong& Gu, Jie& Xiu, Jin& Mi, Tingyan& Dong, Jie& Tiwari, Jyoti Kumar. Traditional Chinese Medicine for Senile Dementia. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1028473
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028473