Traditional Chinese Medicine for Senile Dementia

Joint Authors

Lin, Zhihong
Gu, Jie
Xiu, Jin
Mi, Tingyan
Dong, Jie
Tiwari, Jyoti Kumar

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-07-25

Country of Publication

Egypt

No. of Pages

13

Main Subjects

Medicine

Abstract EN

Traditional Chinese Medicine (TCM) has a 3000 years' history of human use.

A literature survey addressing traditional evidence from human studies was done, with key result that top 10 TCM herb ingredients including Poria cocos, Radix polygalae, Radix glycyrrhizae, Radix angelica sinensis, and Radix rehmanniae were prioritized for highest potential benefit to dementia intervention, related to the highest frequency of use in 236 formulae collected from 29 ancient Pharmacopoeias, ancient formula books, or historical archives on ancient renowned TCM doctors, over the past 10 centuries.

Based on the history of use, there was strong clinical support that Radix polygalae is memory improving.

Pharmacological investigation also indicated that all the five ingredients mentioned above can elicit memory-improving effects in vivo and in vitro via multiple mechanisms of action, covering estrogen-like, cholinergic, antioxidant, anti-inflammatory, antiapoptotic, neurogenetic, and anti-Aβ activities.

Furthermore, 11 active principles were identified, including sinapic acid, tenuifolin, isoliquiritigenin, liquiritigenin, glabridin, ferulic acid, Z-ligustilide, N-methyl-beta-carboline-3-carboxamide, coniferyl ferulate and 11-angeloylsenkyunolide F, and catalpol.

It can be concluded that TCM has a potential for complementary and alternative role in treating senile dementia.

The scientific evidence is being continuously mined to back up the traditional medical wisdom.

American Psychological Association (APA)

Lin, Zhihong& Gu, Jie& Xiu, Jin& Mi, Tingyan& Dong, Jie& Tiwari, Jyoti Kumar. 2011. Traditional Chinese Medicine for Senile Dementia. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1028473

Modern Language Association (MLA)

Lin, Zhihong…[et al.]. Traditional Chinese Medicine for Senile Dementia. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-1028473

American Medical Association (AMA)

Lin, Zhihong& Gu, Jie& Xiu, Jin& Mi, Tingyan& Dong, Jie& Tiwari, Jyoti Kumar. Traditional Chinese Medicine for Senile Dementia. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1028473

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1028473