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Nigella sativa: A Potential Antiosteoporotic Agent
Joint Authors
Shuid, Ahmad Nazrun
Othman, Faizah
Ima-Nirwana, Soelaiman
Mohd Ramli, Elvy Suhana
Mohamed, Norazlina
Muhammad, Norliza
Haji Suhaimi, Farihah
Isa, N. M.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Nigella sativa seeds (NS) has been used traditionally for various illnesses.
The most abundant and active component of NS is thymoquinone (TQ).
Animal studies have shown that NS and TQ may be used for the treatment of diabetes-induced osteoporosis and for the promotion of fracture healing.
The mechanism involved is unclear, but it was postulated that the antioxidative, and anti-inflammatory activities may play some roles in the treatment of osteoporosis as this bone disease has been linked to oxidative stress and inflammation.
This paper highlights studies on the antiosteoporotic effects of NS and TQ, the mechanisms behind these effects and their safety profiles.
NS and TQ were shown to inhibit inflammatory cytokines such as interleukin-1 and 6 and the transcription factor, nuclear factor κB.
NS and TQ were found to be safe at the current dosage for supplementation in human with precautions in children and pregnant women.
Both NS and TQ have shown potential as antiosteoporotic agent but more animal and clinical studies are required to further assess their antiosteoporotic efficacies.
American Psychological Association (APA)
Shuid, Ahmad Nazrun& Mohamed, Norazlina& Isa, N. M.& Othman, Faizah& Haji Suhaimi, Farihah& Mohd Ramli, Elvy Suhana…[et al.]. 2012. Nigella sativa: A Potential Antiosteoporotic Agent. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028477
Modern Language Association (MLA)
Shuid, Ahmad Nazrun…[et al.]. Nigella sativa: A Potential Antiosteoporotic Agent. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1028477
American Medical Association (AMA)
Shuid, Ahmad Nazrun& Mohamed, Norazlina& Isa, N. M.& Othman, Faizah& Haji Suhaimi, Farihah& Mohd Ramli, Elvy Suhana…[et al.]. Nigella sativa: A Potential Antiosteoporotic Agent. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028477
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028477