Antibacterial Activity of Rhodomyrtus tomentosa (Aiton) Hassk. Leaf Extract against Clinical Isolates of Streptococcus pyogenes
Joint Authors
Limsuwan, Surasak
Voravuthikunchai, Supayang Piyawan
Kayser, Oliver
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Ethanol extract of Rhodomyrtus tomentosa (Aiton) Hassk.
leaf was evaluated for antibacterial activity against 47 clinical isolates of Streptococcus pyogenes.
The extract exhibited good anti-S.
pyogenes activity against all the tested isolates with similar minimum inhibitory concentration (MIC, 3.91–62.5 μg mL−1) and minimum bactericidal concentration (MBC, 3.91–62.5 μg mL−1) ranges.
No surviving cells were detected at 16 h after treatment with 8 × MIC of the extract.
The extract-treated cells demonstrated no lysis and cytoplasmic leakage through the bacterial membrane.
Electron micrographs further revealed that the extract did not cause any dramatic changes on the treated cells.
Rhodomyrtone, an isolated compound, exhibited good anti-S.
pyogenes activity (14 isolates), expressed very low MIC (0.39–1.56 μg mL−1) and MBC (0.39-1.56 μg mL−1) values.
Rhodomyrtus tomentosa leaf extract and rhodomyrtone displayed promising antibacterial activity against clinical isolates of S.
pyogenes.
American Psychological Association (APA)
Limsuwan, Surasak& Kayser, Oliver& Voravuthikunchai, Supayang Piyawan. 2012. Antibacterial Activity of Rhodomyrtus tomentosa (Aiton) Hassk. Leaf Extract against Clinical Isolates of Streptococcus pyogenes. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028481
Modern Language Association (MLA)
Limsuwan, Surasak…[et al.]. Antibacterial Activity of Rhodomyrtus tomentosa (Aiton) Hassk. Leaf Extract against Clinical Isolates of Streptococcus pyogenes. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1028481
American Medical Association (AMA)
Limsuwan, Surasak& Kayser, Oliver& Voravuthikunchai, Supayang Piyawan. Antibacterial Activity of Rhodomyrtus tomentosa (Aiton) Hassk. Leaf Extract against Clinical Isolates of Streptococcus pyogenes. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028481
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028481