Chinese Medicine Shenfu Injection for Heart Failure: A Systematic Review and Meta-Analysis
Joint Authors
Lin, Chengren
Cheng, Fafeng
Li, Xu
Liu, Jianxun
Song, Wenting
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-25, 25 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-24
Country of Publication
Egypt
No. of Pages
25
Main Subjects
Abstract EN
Objective.
Heart failure (HF) is a global public health problem.
Early literature studies manifested that Shenfu injection (SFI) is one of the most commonly used traditional Chinese patent medicine for HF in China.
This article intended to systematically evaluate the efficacy and safety of SFI for HF.
Methods.
An extensive search was performed within 6 English and Chinese electronic database up to November 2011.
Ninety-nine randomized controlled trails (RCTs) were collected, irrespective of languages.
Two authors extracted data and assessed the trial quality independently.
RevMan 5.0.2 was used for data analysis.
Results.
Compared with routine treatment and/or device support, SFI combined with routine treatment and/or device support showed better effect on clinical effect rate, mortality, heart rate, NT-proBNP and 6-minute walk distance.
Results in ultrasonic cardiography also showed that SFI combined with routine treatment improved heart function of HF patients.
There were no significant difference in blood pressure between SFI and routine treatment groups.
Adverse events were reported in thirteen trails with thirteen specific symptoms, while no serious adverse effect was reported.
Conclusion.
SFI appear to be effective for treating HF.
However, further rigorously designed RCTs are warranted because of insufficient methodological rigor in the majority of included trials.
American Psychological Association (APA)
Song, Wenting& Cheng, Fafeng& Li, Xu& Lin, Chengren& Liu, Jianxun. 2012. Chinese Medicine Shenfu Injection for Heart Failure: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-25.
https://search.emarefa.net/detail/BIM-1028498
Modern Language Association (MLA)
Song, Wenting…[et al.]. Chinese Medicine Shenfu Injection for Heart Failure: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-25.
https://search.emarefa.net/detail/BIM-1028498
American Medical Association (AMA)
Song, Wenting& Cheng, Fafeng& Li, Xu& Lin, Chengren& Liu, Jianxun. Chinese Medicine Shenfu Injection for Heart Failure: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-25.
https://search.emarefa.net/detail/BIM-1028498
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028498