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Sulfotanshinone Sodium Injection for Unstable Angina Pectoris: A Systematic Review of Randomized Controlled Trials
Joint Authors
Qiu, Xuelan
Miles, Andrew
Sun, Xin
Jiang, Xuehua
Yang, Nan
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
To assess the effect of sulfotanshinone sodium injection for unstable angina.
Methods.
We searched for published and unpublished studies up to June 2011.
We included randomized controlled trials that confoundedly addressed the effect of sulfotanshinone sodium injection in the treatment of unstable angina.
Results.
Twenty-five studies involving 2,377 people were included.
There was no evidence that sulfotanshinone sodium alone had better or worse effects to routine western medicine treatments in improving clinical symptoms (RR 1.00, 95% CI 0.90 to 1.11) and ECG (RR 0.97, 95% CI 0.87 to 1.09).
However, there was evidence that sulfotanshinone sodium combined with western medications was a better treatment option than western medications alone in improving clinical symptoms (RR 1.28, 95% CI 1.23 to 1.3), ECG (RR 1.26, 95% CI 1.18 to 1.35), C-reaction protein (mean difference 2.10, 95% CI 1.63 to 2.58), and IL-6 (mean difference −3.85, 95% CI −4.10 to −3.60).
There was no difference between sulfotanshinone sodium plus western medications and western medications alone affecting mortality (RR 0.50, 95% CI 0.02 to 12.13).
Conclusion.
Compared with western medications alone, sulfotanshinone sodium combined with western medications may provide more benefits for patients with unstable angina.
Further large-scale high-quality trials are warranted.
American Psychological Association (APA)
Qiu, Xuelan& Miles, Andrew& Jiang, Xuehua& Sun, Xin& Yang, Nan. 2012. Sulfotanshinone Sodium Injection for Unstable Angina Pectoris: A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1028502
Modern Language Association (MLA)
Qiu, Xuelan…[et al.]. Sulfotanshinone Sodium Injection for Unstable Angina Pectoris: A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-1028502
American Medical Association (AMA)
Qiu, Xuelan& Miles, Andrew& Jiang, Xuehua& Sun, Xin& Yang, Nan. Sulfotanshinone Sodium Injection for Unstable Angina Pectoris: A Systematic Review of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1028502
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028502