Antimicrobial Activity of Essential Oils against Streptococcus mutans and their Antiproliferative Effects
Joint Authors
Galvão, Lívia Câmara de Carvalho
Duarte, M. C. T.
da Cunha, Marcos Guilherme
Rosalen, Pedro Luiz
Ruiz, Ana Lúcia Tasca Gois
Furletti, Vivian Fernandes
Bersan, Salete Meyre Fernandes
de Alencar, Severino Matias
de Carvalho, João Ernesto
Rehder, V. L. G.
Sartoratto, A.
Ikegaki, Masaharu
Figueira, G. M.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-23
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
This study aimed to evaluate the activity of essential oils (EOs) against Streptococcus mutans biofilm by chemically characterizing their fractions responsible for biological and antiproliferative activity.
Twenty EO were obtained by hydrodistillation and submitted to the antimicrobial assay (minimum inhibitory (MIC) and bactericidal (MBC) concentrations) against S.
mutans UA159.
Thin-layer chromatography and gas chromatography/mass spectrometry were used for phytochemical analyses.
EOs were selected according to predetermined criteria and fractionated using dry column; the resulting fractions were assessed by MIC and MBC, selected as active fractions, and evaluated against S.
mutans biofilm.
Biofilms formed were examined using scanning electron microscopy.
Selected EOs and their selected active fractions were evaluated for their antiproliferative activity against keratinocytes and seven human tumor cell lines.
MIC and MBC values obtained for EO and their active fractions showed strong antimicrobial activity.
Chemical analyses mainly showed the presence of terpenes.
The selected active fractions inhibited S.
mutans biofilm formation (P<0.05) did not affect glycolytic pH drop and were inactive against keratinocytes, normal cell line.
In conclusion, EO showed activity at low concentrations, and their selected active fractions were also effective against biofilm formed by S.
mutans and human tumor cell lines.
American Psychological Association (APA)
Galvão, Lívia Câmara de Carvalho& Furletti, Vivian Fernandes& Bersan, Salete Meyre Fernandes& da Cunha, Marcos Guilherme& Ruiz, Ana Lúcia Tasca Gois& de Carvalho, João Ernesto…[et al.]. 2012. Antimicrobial Activity of Essential Oils against Streptococcus mutans and their Antiproliferative Effects. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1028523
Modern Language Association (MLA)
Galvão, Lívia Câmara de Carvalho…[et al.]. Antimicrobial Activity of Essential Oils against Streptococcus mutans and their Antiproliferative Effects. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-1028523
American Medical Association (AMA)
Galvão, Lívia Câmara de Carvalho& Furletti, Vivian Fernandes& Bersan, Salete Meyre Fernandes& da Cunha, Marcos Guilherme& Ruiz, Ana Lúcia Tasca Gois& de Carvalho, João Ernesto…[et al.]. Antimicrobial Activity of Essential Oils against Streptococcus mutans and their Antiproliferative Effects. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1028523
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028523