In Adjuvant-Induced Arthritic Rats, Acupuncture Analgesic Effects Are Histamine Dependent: Potential Reasons for Acupoint Preference in Clinical Practice
Joint Authors
Zhang, Di
Huang, Meng
Sa, Zhe-yan
Xie, Ying-yuan
Gu, Chen-li
Ding, Guang-Hong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This study investigated whether immediate acupuncture effects in the acupoint are histamine dependent.
Both histamine injection and manual acupuncture stimulation increased the pain threshold (PT) after treatment compared with the model group (P<0.01), producing an analgesic effect.
After pretreatment with clemastine, an H1 receptor antagonist and an antipruritic, the increase in the animals’ pain threshold after acupuncture was suppressed compared with the Acu group (P<0.01); however, there was no interference with the acupuncture-induced degranulation of mast cells.
Pretreatment with disodium cromolyn did not suppress the increase in PT induced by the histamine injection at Zusanli (ST-36).
We conclude that in adjuvant-induced arthritic rats, acupuncture analgesic effects are histamine dependent, and this histamine dependence determines the acupoint preference of acupoints away from the target site in acupuncture practice.
American Psychological Association (APA)
Huang, Meng& Zhang, Di& Sa, Zhe-yan& Xie, Ying-yuan& Gu, Chen-li& Ding, Guang-Hong. 2012. In Adjuvant-Induced Arthritic Rats, Acupuncture Analgesic Effects Are Histamine Dependent: Potential Reasons for Acupoint Preference in Clinical Practice. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028552
Modern Language Association (MLA)
Huang, Meng…[et al.]. In Adjuvant-Induced Arthritic Rats, Acupuncture Analgesic Effects Are Histamine Dependent: Potential Reasons for Acupoint Preference in Clinical Practice. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1028552
American Medical Association (AMA)
Huang, Meng& Zhang, Di& Sa, Zhe-yan& Xie, Ying-yuan& Gu, Chen-li& Ding, Guang-Hong. In Adjuvant-Induced Arthritic Rats, Acupuncture Analgesic Effects Are Histamine Dependent: Potential Reasons for Acupoint Preference in Clinical Practice. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028552
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028552