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The Effects of Velvet Antler of Deer on Cardiac Functions of Rats with Heart Failure following Myocardial Infarction
Joint Authors
Li, Lin
Huang, Li
Shao, Ming-Jing
Zhao, Ming-Jing
Lv, Xi-Ling
Gu, Huan
Zhang, Jiu-Liang
Li, Ge
Cui, Xiang-Ning
Wang, Shuoren
Xu, Hao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Velvet antler of deer (VAD) is a commonly-used kidney-Yang supplementing traditional Chinese medication.
According to the heart-kidney-related theory, heart Yang originates in kidney Yang and heart failure due to heart Yang deficiency can be treated by tonifying kidney Yang.
In this study, we investigated therapeutic effects of VAD on cardiac functions in rats with heart failure following myocardial infarction.
Forty-eight male Wistar rats were subjected either to left coronary artery ligation (N=36) or to sham operation (N=12).
One week after the surgery, rats with heart failure received daily treatment of double-distilled water, captopril or VAD by gavage for consecutively four weeks, while sham-operated animals were given double-distilled water.
Ultrasonic echocardiography was adopted to examine cardiac structural and functional parameters and serum brain natriuretic peptide (BNP) concentration was measured using radioimmunoassay.
We found that VAD partially reversed changes in cardiac functional parameters and serum BNP levels in rats with heart failure.
These results provide further evidence for the heart-kidney-related theory and suggest that VAD might be a potentially alternative and complementary medicine for the treatment of heart failure.
American Psychological Association (APA)
Shao, Ming-Jing& Wang, Shuoren& Zhao, Ming-Jing& Lv, Xi-Ling& Xu, Hao& Li, Lin…[et al.]. 2012. The Effects of Velvet Antler of Deer on Cardiac Functions of Rats with Heart Failure following Myocardial Infarction. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-1028566
Modern Language Association (MLA)
Shao, Ming-Jing…[et al.]. The Effects of Velvet Antler of Deer on Cardiac Functions of Rats with Heart Failure following Myocardial Infarction. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-1028566
American Medical Association (AMA)
Shao, Ming-Jing& Wang, Shuoren& Zhao, Ming-Jing& Lv, Xi-Ling& Xu, Hao& Li, Lin…[et al.]. The Effects of Velvet Antler of Deer on Cardiac Functions of Rats with Heart Failure following Myocardial Infarction. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-1028566
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028566