Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial
Joint Authors
Schetinger, Maria Rosa Chitolina
Dalmora, Sergio L.
Flores, Nélia
Cruz, Ivana de
Araújo, M. C. S.
Farias, J. G.
Rossato, L. V.
Elsenbach, L. I.
Durigon, M.
Morsch, V. M.
Farias, Iria Luiza Gomes
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
To evaluate the effectiveness of Uncaria tomentosa in minimizing the side effects of chemotherapy and improving the antioxidant status of colorectal cancer (CRC) patients, a randomized clinical trial was conducted.
Patients (43) undergoing adjuvant/palliative chemotherapy with 5-Fluorouracil/leucovorin + oxaliplatin (FOLFOX4) were split into two groups: the UT group received chemotherapy plus 300 mg of Uncaria tomentosa daily and the C group received only FOLFOX4 and served as a control.
Blood samples were collected before each of the 6 cycles of chemotherapy, and hemograms, oxidative stress, enzymes antioxidants, immunologic parameters, and adverse events were analyzed.
The use of 300 mg of Uncaria tomentosa daily during 6 cycles of FOLFOX4 did not change the analyzed parameters, and no toxic effects were observed.
American Psychological Association (APA)
Farias, Iria Luiza Gomes& Araújo, M. C. S.& Farias, J. G.& Rossato, L. V.& Elsenbach, L. I.& Dalmora, Sergio L.…[et al.]. 2011. Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028601
Modern Language Association (MLA)
Farias, Iria Luiza Gomes…[et al.]. Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-1028601
American Medical Association (AMA)
Farias, Iria Luiza Gomes& Araújo, M. C. S.& Farias, J. G.& Rossato, L. V.& Elsenbach, L. I.& Dalmora, Sergio L.…[et al.]. Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028601
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028601
