Empirical Likelihood Estimation for Population Pharmacokinetic Study Based on Generalized Linear Model
Joint Authors
Huang, Yuan
Liu, Jun-lin
Lu, Tao
Yan, Fang-Rong
Lin, Jin-Guan
Source
Journal of Applied Mathematics
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-27
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
To obtain efficient estimation of parameters is a major objective in population pharmacokinetic study.
In this paper, we propose an empirical likelihood-based method to analyze the population pharmacokinetic data based on the generalized linear model.
A nonparametric version of the Wilk's theorem for the limiting distributions of the empirical likelihood ratio is derived.
Simulations are conducted to demonstrate the accuracy and efficiency of empirical likelihood method.
An application illustrating our methods and supporting the simulation study results is presented.
The results suggest that the proposed method is feasible for population pharmacokinetic data.
American Psychological Association (APA)
Yan, Fang-Rong& Lin, Jin-Guan& Huang, Yuan& Liu, Jun-lin& Lu, Tao. 2012. Empirical Likelihood Estimation for Population Pharmacokinetic Study Based on Generalized Linear Model. Journal of Applied Mathematics،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1028781
Modern Language Association (MLA)
Yan, Fang-Rong…[et al.]. Empirical Likelihood Estimation for Population Pharmacokinetic Study Based on Generalized Linear Model. Journal of Applied Mathematics No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-1028781
American Medical Association (AMA)
Yan, Fang-Rong& Lin, Jin-Guan& Huang, Yuan& Liu, Jun-lin& Lu, Tao. Empirical Likelihood Estimation for Population Pharmacokinetic Study Based on Generalized Linear Model. Journal of Applied Mathematics. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1028781
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028781