Morphological Characterization of Nanofibers: Methods and Application in Practice
Joint Authors
Michálek, Jiri
Širc, Jakub
Hobzová, Radka
Kostina, Nina
Munzarová, Marcela
Juklíčková, Martina
Lhotka, Miloslav
Kubinová, Šárka
Zajícová, Alena
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-01
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Biomedical applications such as wound dressing for skin regeneration, stem cell transplantation, or drug delivery require special demands on the three-dimensional porous scaffolds.
Besides the biocompatibility and mechanical properties, the morphology is the most important attribute of the scaffold.
Specific surface area, volume, and size of the pores have considerable effect on cell adhesion, growth, and proliferation.
In the case of incorporated biologically active substances, their release is also influenced by the internal structure of nanofibers.
Although many scientific papers are focused on the preparation of nanofibers and evaluation of biological tests, the morphological characterization was described just briefly as service methods.
The aim of this paper is to summarize the methods applicable for morphological characterization of nanofibers and supplement it by the results of our research.
Needleless electrospinning technique was used to prepare nanofibers from polylactide, poly(ε-caprolactone), gelatin, and polyamide.
Scanning electron microscopy was used to evaluate the fiber diameters and to reveal eventual artifacts in the nanofibrous structure.
Nitrogen adsorption/desorption measurements were employed to measure the specific surface areas.
Mercury porosimetry was used to determine total porosities and compare pore size distributions of the prepared samples.
American Psychological Association (APA)
Širc, Jakub& Hobzová, Radka& Kostina, Nina& Munzarová, Marcela& Juklíčková, Martina& Lhotka, Miloslav…[et al.]. 2012. Morphological Characterization of Nanofibers: Methods and Application in Practice. Journal of Nanomaterials،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-1029180
Modern Language Association (MLA)
Širc, Jakub…[et al.]. Morphological Characterization of Nanofibers: Methods and Application in Practice. Journal of Nanomaterials No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-1029180
American Medical Association (AMA)
Širc, Jakub& Hobzová, Radka& Kostina, Nina& Munzarová, Marcela& Juklíčková, Martina& Lhotka, Miloslav…[et al.]. Morphological Characterization of Nanofibers: Methods and Application in Practice. Journal of Nanomaterials. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-1029180
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029180