Fabrication of Photofunctional Nanoporous Membrane and Its Photoinactivation Effect of Vesicular Stomatitis Virus
Joint Authors
Wang, Kang-Kyun
Kim, Bong-Jin
Ko, Si-Hwan
Choi, Dong Hoon
Kim, Yong-Rok
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Fabrication and photophysical study of photofunctional nanoporous alumina membrane (PNAM) were performed, and its application of photodynamic antimicrobial chemotherapy (PACT) was investigated.
Nanoporous alumina membrane (NAM) was fabricated by two-step aluminium anodic oxidation process.
Surface of the fabricated NAM was modified with organo-silane agent to induce covalent bonding between NAM and a photosensitizer (PtCP: [5,10,15-triphenyl-20-(4-methoxycarbonylphenyl)-porphyrin] platinum).
PtCP was covalently bonded to the surface of the modified NAM by nucleophilic acyl substitution reaction process.
The morphology and the photophysical properties of the fabricated PNAM were confirmed with field emission scanning electron microscope (FE-SEM), steady-state spectroscopies, and nanosecond laser-induced time-resolved spectroscopy.
For the efficacy study of PNAM in PACT, an enveloped animal virus, vesicular stomatitis virus (VSV), was utilized as a target organism.
Antiviral effect of the PNAM-PACT was measured by the extent of suppression of plaque-forming units (PFU) after the light irradiation.
In the cultures inoculated with PACT-treated VSV, the suppression of PFU was prominent, which demonstrates that PNAM is a potential bio clean-up tool.
American Psychological Association (APA)
Wang, Kang-Kyun& Kim, Bong-Jin& Ko, Si-Hwan& Choi, Dong Hoon& Kim, Yong-Rok. 2011. Fabrication of Photofunctional Nanoporous Membrane and Its Photoinactivation Effect of Vesicular Stomatitis Virus. Journal of Nanomaterials،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029220
Modern Language Association (MLA)
Wang, Kang-Kyun…[et al.]. Fabrication of Photofunctional Nanoporous Membrane and Its Photoinactivation Effect of Vesicular Stomatitis Virus. Journal of Nanomaterials No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1029220
American Medical Association (AMA)
Wang, Kang-Kyun& Kim, Bong-Jin& Ko, Si-Hwan& Choi, Dong Hoon& Kim, Yong-Rok. Fabrication of Photofunctional Nanoporous Membrane and Its Photoinactivation Effect of Vesicular Stomatitis Virus. Journal of Nanomaterials. 2011. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029220
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029220