![](/images/graphics-bg.png)
Bifunctional Silica-Coated Superparamagnetic FePt Nanoparticles for FluorescenceMR Dual Imaging
Joint Authors
Hsu, Chia-Yen
Tsai, Jai-Lin
Lai, Syu-Ming
Tsai, Tsiao-Yu
Liao, Ming-Yuan
Lai, Ping-Shan
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Recently, superparamagnetic chemically disordered face-centered cubic (fcc) FePt nanoparticles have been demonstrated as superior negative contrast agents for magnetic resonance imaging (MRI).
However, their low intracellular labeling efficiency has limited the potential usage and the nanotoxicity of the particles requires attention.
We have developed fluorescein isothiocyanate-incorporated silica-coated FePt (FePt@SiO2-FITC) nanoparticles that exhibited not only a significant T1 and T2 MR contrast abilities but also a fluorescent property without significant cytotoxicities.
These results suggest that silica-coated superparamagnetic FePt nanoparticles are potential nanodevices for the combination of fluorescence and MRI contrast used for cancer diagnosis.
American Psychological Association (APA)
Lai, Syu-Ming& Tsai, Tsiao-Yu& Hsu, Chia-Yen& Tsai, Jai-Lin& Liao, Ming-Yuan& Lai, Ping-Shan. 2012. Bifunctional Silica-Coated Superparamagnetic FePt Nanoparticles for FluorescenceMR Dual Imaging. Journal of Nanomaterials،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029249
Modern Language Association (MLA)
Lai, Syu-Ming…[et al.]. Bifunctional Silica-Coated Superparamagnetic FePt Nanoparticles for FluorescenceMR Dual Imaging. Journal of Nanomaterials No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1029249
American Medical Association (AMA)
Lai, Syu-Ming& Tsai, Tsiao-Yu& Hsu, Chia-Yen& Tsai, Jai-Lin& Liao, Ming-Yuan& Lai, Ping-Shan. Bifunctional Silica-Coated Superparamagnetic FePt Nanoparticles for FluorescenceMR Dual Imaging. Journal of Nanomaterials. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029249
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029249