Gold Nanorod-Mediated Photothermal Modulation for Localized Ablation of Cancer Cells
Joint Authors
Hong, Yoochan
Yoon, Dae Sung
Yang, Jaemoon
Lee, Eugene
Choi, Jihye
Oh, Seung Jae
Haam, Seungjoo
Huh, Yong-Min
Suh, Jin-Suck
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We estimated the photothermal transduction efficiency of gold nanorod (GNR) solutions for different GNR concentrations and irradiation laser power.
In particular, we verified that the degree of cell death area could be modulated by GNR concentration and irradiation laser power.
The efficacy of GNR-produced photothermal ablation of cancer cells was evaluated by irradiating GNRs in the presence of MDA-MB-231 breast cancer cells with a near-infrared (NIR) laser at different laser power densities and irradiation times.
GNR-induced photothermal ablation was applied successfully to cancer cells at various NIR laser power densities and irradiation times and was characterized with live-dead cell staining.
Through these techniques, we established the system for not only verification of induced photothermal effect using NIR laser and thermocouple, but also identification of uptake efficiency for GNRs and cell viability using dark field and fluorescence imaging, respectively.
American Psychological Association (APA)
Hong, Yoochan& Lee, Eugene& Choi, Jihye& Oh, Seung Jae& Haam, Seungjoo& Huh, Yong-Min…[et al.]. 2012. Gold Nanorod-Mediated Photothermal Modulation for Localized Ablation of Cancer Cells. Journal of Nanomaterials،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029288
Modern Language Association (MLA)
Hong, Yoochan…[et al.]. Gold Nanorod-Mediated Photothermal Modulation for Localized Ablation of Cancer Cells. Journal of Nanomaterials No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1029288
American Medical Association (AMA)
Hong, Yoochan& Lee, Eugene& Choi, Jihye& Oh, Seung Jae& Haam, Seungjoo& Huh, Yong-Min…[et al.]. Gold Nanorod-Mediated Photothermal Modulation for Localized Ablation of Cancer Cells. Journal of Nanomaterials. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029288
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029288