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The Application of Biophysical Techniques to Study Antimicrobial Peptides
Joint Authors
Torcato, Inês M.
Henriques, Sónia T.
Castanho, Miguel
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The increasing bacteria resistance to conventional antibiotics has led to the need for alternative therapies.
Being part of the human innate defence system and with a broad spectrum of activity against bacteria, viruses, protozoa, and cancer cells, antimicrobial peptides (AMPs) are a very promising alternative.
The mechanism of action of AMPs seems to broadly correlate with their ability to target the bacterial cell membrane.
To understand and improve their effect, it is of major importance to unravel their mechanism of action and, in particular, to understand the peptide-membrane binding.
Several biophysical techniques such as fluorescence spectroscopy, circular dichroism, zeta potential determination, and atomic force microscopy can be used to achieve this goal.
Characteristics of AMPs-membranes interactions and the use of these biophysical techniques will be discussed.
American Psychological Association (APA)
Torcato, Inês M.& Castanho, Miguel& Henriques, Sónia T.. 2012. The Application of Biophysical Techniques to Study Antimicrobial Peptides. Journal of Spectroscopy،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1029353
Modern Language Association (MLA)
Torcato, Inês M.…[et al.]. The Application of Biophysical Techniques to Study Antimicrobial Peptides. Journal of Spectroscopy No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-1029353
American Medical Association (AMA)
Torcato, Inês M.& Castanho, Miguel& Henriques, Sónia T.. The Application of Biophysical Techniques to Study Antimicrobial Peptides. Journal of Spectroscopy. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1029353
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029353