Proteomic Analyses of the Vitreous Humour
Joint Authors
Semeraro, Francesco
Romano, Mario R.
Kalirai, Helen
Coupland, Sarah E.
Damato, Bertil E.
Angi, Martina
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The human vitreous humour (VH) is a transparent, highly hydrated gel, which occupies the posterior segment of the eye between the lens and the retina.
Physiological and pathological conditions of the retina are reflected in the protein composition of the VH, which can be sampled as part of routine surgical procedures.
Historically, many studies have investigated levels of individual proteins in VH from healthy and diseased eyes.
In the last decade, proteomics analyses have been performed to characterise the proteome of the human VH and explore networks of functionally related proteins, providing insight into the aetiology of diabetic retinopathy and proliferative vitreoretinopathy.
Recent proteomic studies on the VH from animal models of autoimmune uveitis have identified new signalling pathways associated to autoimmune triggers and intravitreal inflammation.
This paper aims to guide biological scientists through the different proteomic techniques that have been used to analyse the VH and present future perspectives for the study of intravitreal inflammation using proteomic analyses.
American Psychological Association (APA)
Angi, Martina& Kalirai, Helen& Coupland, Sarah E.& Damato, Bertil E.& Semeraro, Francesco& Romano, Mario R.. 2012. Proteomic Analyses of the Vitreous Humour. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029370
Modern Language Association (MLA)
Angi, Martina…[et al.]. Proteomic Analyses of the Vitreous Humour. Mediators of Inflammation No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1029370
American Medical Association (AMA)
Angi, Martina& Kalirai, Helen& Coupland, Sarah E.& Damato, Bertil E.& Semeraro, Francesco& Romano, Mario R.. Proteomic Analyses of the Vitreous Humour. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029370
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029370