The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting
Joint Authors
Kolackova, Martina
Kunes, P.
Holubcova, Z.
Svitek, Vladimir
Mandak, Jiri
Krejsek, Jan
Lonsky, Vladimir
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Interleukin-10 (IL-10) is considered to be a cytokine with potent anti-inflammatory properties, which have been previously linked to increased incidence of sepsis.
The level of IL-10 is elevated by cardiac surgery when cardiopulmonary bypass (CPB) and methylprednisolone are used.
In our study, we compare the level of IL-10, IL-10 Receptor (IL-10R), and percentage of neutrophils between two groups of cardiac surgical patients undergoing Coronary Artery Bypass Grafting, both of which were not given methylprednisolone.
The first group was operated with conventional CPB, while the second group was operated with minimally invasive CPB (mini-CPB).
We detected enhanced level of IL-10 during surgery and at the end of surgery in both groups of patients.
While no correlation between IL-10 and IL10R was found, IL-10 was positively correlated with increased percentage of neutrophils at the time points when the level of IL-10 peaked.
American Psychological Association (APA)
Kolackova, Martina& Krejsek, Jan& Svitek, Vladimir& Kunes, P.& Mandak, Jiri& Holubcova, Z.…[et al.]. 2012. The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1029371
Modern Language Association (MLA)
Kolackova, Martina…[et al.]. The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting. Mediators of Inflammation No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-1029371
American Medical Association (AMA)
Kolackova, Martina& Krejsek, Jan& Svitek, Vladimir& Kunes, P.& Mandak, Jiri& Holubcova, Z.…[et al.]. The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1029371
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029371