PGD Synthase and PGD2 in Immune Resposne
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
PGD2 is formed from arachidonic acid by successive enzyme reactions: oxygenation of arachidonic acid to PGH2, a common precursor of various prostanoids, catalyzed by cyclooxygenase, and isomerization of PGH2 to PGD2 by PGD synthases (PGDSs).
PGD2 can be either pro- or anti-inflammatory depending on disease process and etiology.
The anti-inflammatory and immunomodulatory attributes of PGDS/PGD2 provide opportunities for development of novel therapeutic approaches for resistant infections and refractory inflammatory diseases.
This paper highlights the role of PGD synthases and PGD2 in immune inflammatory response.
American Psychological Association (APA)
Joo, Myungsoo& Sadikot, Ruxana. 2012. PGD Synthase and PGD2 in Immune Resposne. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1029407
Modern Language Association (MLA)
Joo, Myungsoo& Sadikot, Ruxana. PGD Synthase and PGD2 in Immune Resposne. Mediators of Inflammation No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1029407
American Medical Association (AMA)
Joo, Myungsoo& Sadikot, Ruxana. PGD Synthase and PGD2 in Immune Resposne. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1029407
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029407
