Association of Mitral Annulus Calcification with High-Sensitivity C-Reactive Protein, Which Is a Marker of Inflammation
Joint Authors
Kurtoğlu, Ertuğrul
Korkmaz, Hasan
Aktürk, Erdal
Yılmaz, Mücahid
Uçkan, Ahmet
Altas, Yakup
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
There are limited clinical data revealing the relationship between mitral annular calcification (MAC) and systemic inflammation.
The goal of the present study was to compare high-sensitivity C-reactive protein (hs-CRP) levels in patients with and without MAC and investigate the relationship between MAC and hs-CRP.
Methods.
One hundred patients with MAC who underwent transthoracic echocardiography (TTE) and 100 age-matched controls without MAC who underwent TTE were included in our study.
Hs-CRP levels were compared between groups.
Results.
Prevalence of female gender, hypertension, and coronary artery disease were significantly higher in the MAC group than in the control group (64% versus 45%, P=0.007, 42% versus 28%, P=0.03 and 37% versus 18%, P=0.003, resp.).
On multivariate analysis, age, gender, and coronary artery disease were the only independent predictors of MAC.
The levels of hs-CRP were higher in the MAC group than in the control group (2.02±0.35 versus 1.43±0.47 mg/dl, P<0.001).
This increase in hs-CRP levels in the MAC group persisted in patients without hypertension, coronary artery disease, and in male patients when compared to the control group.
Conclusions.
Our study demonstrated that hs-CRP, which is a sensitive marker of systemic inflammation, increased in patients with MAC.
American Psychological Association (APA)
Kurtoğlu, Ertuğrul& Korkmaz, Hasan& Aktürk, Erdal& Yılmaz, Mücahid& Altas, Yakup& Uçkan, Ahmet. 2012. Association of Mitral Annulus Calcification with High-Sensitivity C-Reactive Protein, Which Is a Marker of Inflammation. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1029421
Modern Language Association (MLA)
Kurtoğlu, Ertuğrul…[et al.]. Association of Mitral Annulus Calcification with High-Sensitivity C-Reactive Protein, Which Is a Marker of Inflammation. Mediators of Inflammation No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1029421
American Medical Association (AMA)
Kurtoğlu, Ertuğrul& Korkmaz, Hasan& Aktürk, Erdal& Yılmaz, Mücahid& Altas, Yakup& Uçkan, Ahmet. Association of Mitral Annulus Calcification with High-Sensitivity C-Reactive Protein, Which Is a Marker of Inflammation. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1029421
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1029421